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MDS1 and EVI1 Complex Locus Products

(MDS1 and EVI1 Complex Locus (MECOM))

Categories

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].

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Featured MDS1 and EVI1 Complex Locus Categories

MDS1 and EVI1 Complex Locus Antibodies

High quality antibodies with extensive validation data.

MDS1 and EVI1 Complex Locus ELISA Kits

Reliable ELISA kits for a wide range of species.

MDS1 and EVI1 Complex Locus Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MDS1 and EVI1 Complex Locus Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7074575
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN2777403
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6263184
Quantity 100 μL
Datasheet Datasheet

Recommended MDS1 and EVI1 Complex Locus ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1141785
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1141786
Quantity 96 tests
Datasheet Datasheet

Recommended MDS1 and EVI1 Complex Locus Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310620
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310610
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310612
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MDS1 and EVI1 Complex Locus products

Ghisi, Kats, Masson, Li, Kratina, Vidacs, Gilan, Doyle, Newbold, Bolden, Fairfax, de Graaf, Firth, Zuber, Dickins, Corcoran, Dawson, Belz, Johnstone: "Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia." in: Cancer cell, Vol. 30, Issue 1, pp. 59-74, (2016) (PubMed).

Shen, Chen, Zhang, Yin, Ning, Su, Lin, Song, Wang, Ma, Zhao, Yu, Zhang: "The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia." in: PLoS genetics, Vol. 12, Issue 9, pp. e1006259, (2016) (PubMed).

Cristóbal, Garcia-Orti, Cirauqui, Cortes-Lavaud, García-Sánchez, Calasanz, Odero: "Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia." in: Haematologica, Vol. 97, Issue 4, pp. 543-50, (2012) (PubMed).

Konrad, Karger, Hackl, Schwarzinger, Herbacek, Wieser: "Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes." in: Journal of leukocyte biology, Vol. 86, Issue 4, pp. 813-22, (2009) (PubMed).

Synonyms and alternative names related to MDS1 and EVI1 Complex Locus

MDS1 and EVI1 complex locus (MECOM), MDS1 and EVI1 complex locus (Mecom), MDS1 and EVI1 complex locus (mecom), MDS1 and EVI1 complex locus L homeolog (mecom.L), MDS1 and EVI1 complex locus S homeolog (mecom.S), AML1-EVI-1, D630039M04Rik, Evi-1, evi-1, EVI1, Evi1, evi1, evi1-B, im:7140716, Jbo, Mds, MDS1, Mds1, MDS1-EVI1, Mds1-Evi1, mecom, mecom-a, mecom-b, PRDM3, Prdm3, prdm3, xEvi-1, Znfpr1b1

Protein level used designations for MDS1 and EVI1 Complex Locus

  • AML1-EVI-1 fusion protein
  • MDS1 and EVI1 complex locus protein EVI1
  • MDS1 and EVI1 complex locus protein MDS1
  • ecotropic virus integration site 1 protein homolog
  • myelodysplasia syndrome-associated protein 1
  • oncogene EVI1
  • zinc finger protein Evi1
  • ecotropic viral integration site 1
  • ecotropic virus integration site 1 protein
  • myelodysplasia syndrome 1 homolog
  • myelodysplasia syndrome 1 protein homolog
  • PR domain containing 3
  • MDS1 and EVI1 complex locus
  • MDS1 and EVI1 complex locus protein EVI1-like
  • MDS1 and EVI1 complex locus protein EVI1-A
  • ecotropic virus integration site 1 protein homolog-A
  • myelodysplasia syndrome 1-ectopic viral integration site 1
  • Ecotropic virus integration site 1 protein homolog-B
  • MDS1 and EVI1 complex locus protein EVI1-B
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