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MDM4-binding Protein Proteins

(Mdm4-binding Protein (MDM4))

This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latter's degradation. So this protein can reverse MDM2-targeted degradation of p53, while maintaining suppression of p53 transactivation and apoptotic functions. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2011].

recommended

MDM4-binding Protein Protein (AA 1-137) (His tag) (ABIN7123869)

MDM4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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recommended

MDM4-binding Protein Protein (AA 1-300) (His tag) (ABIN7123868)

MDM4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB

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recommended

MDM4-binding Protein Protein (AA 381-490) (GST tag) (ABIN1310606)

MDM4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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MDM4-binding Protein Proteins by Origin

Find MDM4-binding Protein Proteins for a variety of species such as anti-Human MDM4-binding Protein, anti-Cow MDM4-binding Protein, anti-Mouse MDM4-binding Protein. The species listed below are among those available. Click on a link to go to the corresponding products.

MDM4-binding Protein Proteins by Source

Here you will find MDM4-binding Protein Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

MDM4-binding Protein Proteins by Protein Type

Here you can find MDM4-binding Protein Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

MDM4-binding Protein Proteins by Application

Find MDM4-binding Protein Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MDM4-binding Protein Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

MDM4-binding Protein Protein (AA 1-137) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123869

Quantity 50 μg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-300) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123868

Quantity 50 μg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 381-490) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310606

Quantity 10 μg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-490) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1310604

Quantity 10 μg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-490) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3083685

Quantity 1 mg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-489) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3131620

Quantity 1 mg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-137) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6700262

Quantity 50 μg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-475) (His tag)

Reactivity Xenopus laevis

Source Yeast

Validations

Cat. No. ABIN1677564

Quantity 1 mg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-490) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1634191

Quantity 1 mg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-491) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1622023

Quantity 1 mg

Datasheet Datasheet

MDM4-binding Protein Protein (AA 1-496) (His tag)

Reactivity Zebrafish (Danio rerio)

Source Yeast

Validations

Cat. No. ABIN1678275

Quantity 1 mg

Datasheet Datasheet

Aliases for MDM4-binding Protein Proteins

MDM4, p53 regulator S homeolog (mdm4.S) Proteins
MDM4, p53 regulator (MDM4) Proteins
MDM4, p53 regulator (Mdm4) Proteins
MDM4, p53 regulator (mdm4) Proteins
transformed mouse 3T3 cell double minute 4 (Mdm4) Proteins
4933417N07Rik Proteins
AA414968 Proteins
AL023055 Proteins
AU018793 Proteins
AU021806 Proteins
C85810 Proteins
HDMX Proteins
mdmx Proteins
MDMX Proteins
Mdmx Proteins
MRP1 Proteins
wu:fa09h09 Proteins
wu:fi33d10 Proteins

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MDM4-binding Protein Proteins by Origin

MDM4-binding Protein Proteins by Source

MDM4-binding Protein Proteins by Protein Type

MDM4-binding Protein Proteins by Application

Popular MDM4-binding Protein Proteins

Aliases for MDM4-binding Protein Proteins

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