MCU Products
(Mitochondrial Calcium Uniporter (MCU))
Categories
This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
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Featured MCU Categories
MCU Antibodies
High quality antibodies with extensive validation data.
MCU ELISA Kits
Reliable ELISA kits for a wide range of species.
MCU Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MCU Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN7268549
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, WB
Validations
- (3)
Cat. No.
ABIN7146314
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC, WB
Validations
- (2)
Cat. No.
ABIN6260526
Quantity
100 μL
Datasheet
Datasheet
Recommended MCU ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN1744117
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1742896
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1773800
Quantity
96 tests
Datasheet
Datasheet
Recommended MCU Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310583
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN3116679
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2713279
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our MCU products
: "Effects of luteolin on regulatory proteins and enzymes for myocyte calcium circulation in hypothermic preserved rat heart." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1433-1441, (2018) (PubMed).: "Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter." in: EMBO reports, Vol. 16, Issue 10, pp. 1318-33, (2015) (PubMed).
: "Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability." in: Journal of proteome research, Vol. 13, Issue 5, pp. 2620-36, (2014) (PubMed).
: "Reconstitution of the mitochondrial calcium uniporter in yeast." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. 8985-90, (2014) (PubMed).
: "Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity." in: Nature medicine, Vol. 20, Issue 12, pp. 1427-35, (2014) (PubMed).
: "Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. ..." in: Nature genetics, Vol. 46, Issue 2, pp. 188-93, (2014) (PubMed).
: "Mitochondrial calcium uniporter MCU supports cytoplasmic Ca2+ oscillations, store-operated Ca2+ entry and Ca2+-dependent gene expression in response to receptor stimulation." in: PLoS ONE, Vol. 9, Issue 7, pp. e101188, (2014) (PubMed).
: "Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals." in: Nature communications, Vol. 4, pp. 2034, (2013) (PubMed).
: "The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter." in: Nature cell biology, Vol. 15, Issue 12, pp. 1464-72, (2013) (PubMed).
: "Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter." in: Nature, Vol. 476, Issue 7360, pp. 341-5, (2011) (PubMed).
Synonyms and alternative names related to MCU
mitochondrial calcium uniporter (MCU), mitochondrial calcium uniporter (Mcu), 2010012O16Rik, AV064928, C10orf42, CCDC109A, Ccdc109a, D130073L02Rik, Gm64Protein level used designations for MCU
- calcium uniporter protein, mitochondrial
- coiled-coil domain-containing protein 109A
- coiled-coil domain containing 109A
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