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MCPH1 Products

(Microcephalin 1 (MCPH1))
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010].

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Featured MCPH1 Categories

MCPH1 Antibodies

High quality antibodies with extensive validation data.

MCPH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MCPH1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MCPH1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7159700
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257347
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7246046
Quantity 200 μL
Datasheet Datasheet

Recommended MCPH1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1142500
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142501
Quantity 96 tests
Datasheet Datasheet

Recommended MCPH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310573
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310571
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093726
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MCPH1 products

Venkatesh, Nagashri, Swamy, Mohiyuddin, Gopinath, Kumar: "Primary microcephaly gene MCPH1 shows signatures of tumor suppressors and is regulated by miR-27a in oral squamous cell carcinoma." in: PLoS ONE, Vol. 8, Issue 3, pp. e54643, (2013) (PubMed).

Richardson, Shaaban, Kamal, Alisary, Walker, Ellis, Speirs, Green, Bell: "Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation." in: Breast cancer research and treatment, Vol. 127, Issue 3, pp. 639-48, (2011) (PubMed).

Synonyms and alternative names related to MCPH1

microcephalin 1 (Mcph1), microcephalin 1 S homeolog (mcph1.S), microcephalin 1 (MCPH1), microcephalin 1 (mcph1), microcephaly, primary autosomal recessive 1 (Mcph1), 5430437K10Rik, brit1, BRIT1, D030046N04Rik, MCPH1, mct, MCT, MGC83773, MGC148665, RGD1560642

Protein level used designations for MCPH1

  • microcephaly, primary autosomal recessive 1
  • microcephalin 1
  • microcephalin
  • BRCT-repeat inhibitor of TERT expression 1
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