MCM8 Products
(Minichromosome Maintenance Deficient 8 (MCM8))
Categories
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured MCM8 Categories
MCM8 Antibodies
High quality antibodies with extensive validation data.
MCM8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MCM8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN309831
Quantity
25 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6737804
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN529702
Quantity
100 μg
Datasheet
Datasheet
Recommended MCM8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6211736
Quantity
96 tests
Datasheet
Datasheet
Recommended MCM8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1310565
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1990369
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505291
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MCM8 products
: "RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination." in: Molecular cell, Vol. 66, Issue 5, pp. 622-634.e8, (2017) (PubMed).: "The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination." in: Molecular and cellular biology, Vol. 33, Issue 8, pp. 1632-44, (2013) (PubMed).
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
: "Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix: a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues." in: Human pathology, Vol. 40, Issue 1, pp. 41-9, (2008) (PubMed).
Synonyms and alternative names related to MCM8
minichromosome maintenance 8 homologous recombination repair factor (MCM8), minichromosome maintenance 8 homologous recombination repair factor (Mcm8), minichromosome maintenance 8 homologous recombination repair factor L homeolog (mcm8.L), 5730432L01Rik, C20orf154, dJ967N21.5Protein level used designations for MCM8
- DNA helicase MCM8
- DNA replication licensing factor MCM8
- MCM8 minichromosome maintenance deficient 8
- REC homolog
- minichromosome maintenance 8
- minichromosome maintenance deficient 8
- Minichromosome maintenance 8
You are here:
