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MBTPS1 Products

(Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq, Jul 2008].

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Featured MBTPS1 Categories

MBTPS1 Antibodies

High quality antibodies with extensive validation data.

MBTPS1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MBTPS1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7256896
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6259458
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7166091
Quantity 100 μg
Datasheet Datasheet

Recommended MBTPS1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310499
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310498
Quantity 25 μg
Datasheet Datasheet

Synonyms and alternative names related to MBTPS1

membrane bound transcription factor peptidase, site 1 (MBTPS1), membrane-bound transcription factor peptidase, site 1 (Mbtps1), 0610038M03Rik, AV003995, mKIAA0091, PCSK8, S1P, S1p, SKI-1, Ski-1, Ski1

Protein level used designations for MBTPS1

  • endopeptidase S1P
  • membrane-bound transcription factor site-1 protease
  • site-1 protease
  • subtilisin/kexin isozyme-1
  • S1P endopeptidase
  • membrane-bound transcription factor protease, site 1
  • sterol-regulated luminal protease
  • subtilisin/kexin isozyme 1
  • subtilisin/kexin isozyme SKI-1
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