MBP Products
(Myelin Basic Protein (MBP))
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The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008].
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Featured MBP Categories
MBP Antibodies
High quality antibodies with extensive validation data.
MBP ELISA Kits
Reliable ELISA kits for a wide range of species.
MBP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MBP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, ICC, FACS
Validations
- (2)
- (7)
Cat. No.
ABIN969279
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7442024
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7259298
Quantity
200 μL
Datasheet
Datasheet
Recommended MBP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6957933
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957934
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957935
Quantity
96 tests
Datasheet
Datasheet
Recommended MBP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2565162
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390814
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413958
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MBP products
: "Biosensors and nanobiosensors for rapid detection of autoimmune diseases: a review." in: Mikrochimica acta, Vol. 186, Issue 12, pp. 838, (2020) (PubMed).: "Conductive Hydroxyethyl Cellulose/Soy Protein Isolate/Polyaniline Conduits for Enhancing Peripheral Nerve Regeneration via Electrical Stimulation." in: Frontiers in bioengineering and biotechnology, Vol. 8, pp. 709, (2020) (PubMed).
: "A blend containing docosahexaenoic acid, arachidonic acid, vitamin B12, vitamin B9, iron and sphingomyelin promotes myelination in an in vitro model." in: Nutritional neuroscience, pp. 1-15, (2019) (PubMed).
: "NET Formation in Bullous Pemphigoid Patients With Relapse Is Modulated by IL-17 and IL-23 Interplay." in: Frontiers in immunology, Vol. 10, pp. 701, (2019) (PubMed).
: "Prior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable." in: Pediatric rheumatology online journal, Vol. 16, Issue 1, pp. 3, (2018) (PubMed).
: "Sox2 Is Essential for Oligodendroglial Proliferation and Differentiation during Postnatal Brain Myelination and CNS Remyelination." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 7, pp. 1802-1820, (2018) (PubMed).
: "The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord." in: Molecular neurobiology, (2018) (PubMed).
: "Can Recognition of Spinal Ischemia Be Improved? Application of Motor-Evoked Potentials, Serum Markers, and Breath Gas Analysis in an Acutely Instrumented Pig Model." in: Annals of vascular surgery, Vol. 49, pp. 191-205, (2018) (PubMed).
: "IgG synthesis rate and anti-myelin oligodendrocyte glycoprotein antibody in CSF may be associated with the onset of CNS demyelination after haplo-HSCT." in: Annals of hematology, Vol. 97, Issue 8, pp. 1399-1406, (2018) (PubMed).
: "Neuroprotective effect of ischemic postconditioning on sciatic nerve transection." in: Neural regeneration research, Vol. 13, Issue 3, pp. 492-496, (2018) (PubMed).
Synonyms and alternative names related to MBP
myelin basic protein (MBP), myelin basic protein (Mbp), myelin basic protein a (mbpa), myelin basic protein (mbp), myelin basic protein L homeolog (mbp.L), C76307, cb274, fj33b11, golli-mbp, Hmbpr, mbp, Mbps, MGC115135, mld, R75289, shi, wu:fj33b11, wu:fq15b02, zgc:136630Protein level used designations for MBP
- myelin A1 protein
- myelin membrane encephalitogenic protein
- myelin deficient
- shiverer
- Golli-Mbp; myelin basic protein
- Golli-Mbp; myelin basic protein; myelin basic protein S
- MBP S
- myelin basic protein Golli-mbp
- myelin basic protein S
- myelin basic protein
- Golli-mbp
- 20 kDa microtubule-stabilizing protein
- microtubule-stabilizing protein
- Myelin A1 protein
- Myelin P1 protein
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