MBNL1 Products
(Muscleblind-like Protein 1 (MBNL1))
Categories
Involved in pre-mRNA alternative splicing regulation. Binds to CUG triplet repeat in RNA (By similarity).
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Featured MBNL1 Categories
MBNL1 Antibodies
High quality antibodies with extensive validation data.
MBNL1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MBNL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MBNL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN561753
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN574297
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7264101
Quantity
200 μL
Datasheet
Datasheet
Recommended MBNL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1143401
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1143402
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1143400
Quantity
96 tests
Datasheet
Datasheet
Recommended MBNL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (2)
Cat. No.
ABIN2725584
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310480
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310482
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MBNL1 products
: "Muscleblind-like 1 is required for normal heart valve development in vivo." in: BMC developmental biology, Vol. 15, pp. 36, (2015) (PubMed).: "Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1)." in: PLoS ONE, Vol. 9, Issue 4, pp. e95957, (2014) (PubMed).
: "Muscleblind-like 1 activates insulin receptor exon 11 inclusion by enhancing U2AF65 binding and splicing of the upstream intron." in: Nucleic acids research, Vol. 42, Issue 3, pp. 1893-903, (2014) (PubMed).
: "Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25426-37, (2010) (PubMed).
: "A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16068-73, (2009) (PubMed).
: "Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2." in: Neuromuscular disorders : NMD, Vol. 19, Issue 5, pp. 335-43, (2009) (PubMed).
: "Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle." in: The American journal of pathology, Vol. 174, Issue 1, pp. 216-27, (2009) (PubMed).
: "Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1." in: Nature structural & molecular biology, Vol. 15, Issue 12, pp. 1343-51, (2008) (PubMed).
: "MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T." in: RNA (New York, N.Y.), Vol. 13, Issue 12, pp. 2238-51, (2007) (PubMed).
: "Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources." in: Antioxidants & redox signaling, Vol. 7, Issue 9-10, pp. 1140-9, (2005) (PubMed).
Synonyms and alternative names related to MBNL1
muscleblind like splicing regulator 1 (MBNL1), muscleblind like splicing regulator 1 (mbnl1), muscleblind-like splicing regulator 1 (mbnl1), muscleblind like splicing factor 1 (Mbnl1), muscleblind-like splicing regulator 1 (Mbnl1), EXP, EXP35, EXP40, EXP42, Mbnl, MBNL, MBNL1, mKIAA0428, zgc:153954Protein level used designations for MBNL1
- muscleblind-like
- muscleblind-like (Drosophila)
- muscleblind-like protein 1
- muscleblind-like 1
- triplet-expansion RNA-binding protein
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