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Matrix Metallopeptidase 14 (Membrane-inserted) Products

(Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily\; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008].

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Featured Matrix Metallopeptidase 14 (Membrane-inserted) Categories

Matrix Metallopeptidase 14 (Membrane-inserted) Antibodies

High quality antibodies with extensive validation data.

Matrix Metallopeptidase 14 (Membrane-inserted) ELISA Kits

Reliable ELISA kits for a wide range of species.

Matrix Metallopeptidase 14 (Membrane-inserted) Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Matrix Metallopeptidase 14 (Membrane-inserted) Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7434626
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (6)
Cat. No. ABIN5542659
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (5)
Cat. No. ABIN6263294
Quantity 100 μL
Datasheet Datasheet

Recommended Matrix Metallopeptidase 14 (Membrane-inserted) ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6957686
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963004
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962604
Quantity 96 tests
Datasheet Datasheet

Recommended Matrix Metallopeptidase 14 (Membrane-inserted) Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7092827
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123856
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311068
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Matrix Metallopeptidase 14 (Membrane-inserted) products

MacKeil, Brzezinska, Burke-Kleinman, Craig, Nicol, Maurice: "A PKA/cdc42 Signaling Axis Restricts Angiogenic Sprouting by Regulating Podosome Rosette Biogenesis and Matrix Remodeling." in: Scientific reports, Vol. 9, Issue 1, pp. 2385, (2019) (PubMed).

Tang, Pei, Yang, Wang, Wang, Gao, Li, Yang, Yang: "The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway." in: Scientific reports, Vol. 6, pp. 29975, (2018) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Du, Wang, Tan, Li, Huang, Huang, Yang, Zhang, Wang, Huang, Huang: "Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice." in: Journal of the American Heart Association, Vol. 5, Issue 12, (2017) (PubMed).

Li, Li, Zeng, Liu, Yang: "H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression." in: Renal failure, Vol. 39, Issue 1, pp. 265-272, (2017) (PubMed).

Morgan, Behbahani-Nejad, Endres, Amin, Lepore, Du, Urquhart, Chung, Fox: "Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162008, (2016) (PubMed).

Shi, Wang, Zhang, Li, Guo, Li, Chen: "Effect of lentivirus-mediated uPA silencing on the proliferation and apoptosis of chondrocytes and the expression of MMPs." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 35, Issue 1, pp. 111-6, (2015) (PubMed).

Ceriello, La Sala, De Nigris, Pujadas, Testa, Uccellatore, Genovese: "GLP-1 reduces metalloproteinase-14 and soluble endoglin induced by both hyperglycemia and hypoglycemia in type 1 diabetes." in: Endocrine, Vol. 50, Issue 2, pp. 508-11, (2015) (PubMed).

Sathyamoorthy, Tezera, Walker, Brilha, Saraiva, Mauri, Wilkinson, Friedland, Elkington: "Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 882-91, (2015) (PubMed).

Loskutov, Kozyulina, Kozyreva, Ice, Jones, Roston, Smolkin, Ivanov, Wysolmerski, Pugacheva: "NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer." in: Oncogene, Vol. 34, Issue 28, pp. 3662-75, (2015) (PubMed).

Synonyms and alternative names related to Matrix Metallopeptidase 14 (Membrane-inserted)

matrix metallopeptidase 14 (MMP14), matrix metallopeptidase 14 (mmp14), matrix metallopeptidase 14 (membrane-inserted) (Mmp14), matrix metallopeptidase 14 (Mmp14), matrix metallopeptidase 14b (membrane-inserted) (mmp14b), matrix metallopeptidase 14a (membrane-inserted) (mmp14a), matrix metallopeptidase 14 L homeolog (mmp14.L), AI325305, cb386, MMP-14, MMP-X1, mmp-x1, MMP1, mmp14, MT-MMP, MT-MMP-1, MT-MMP 1, MT-MMPbeta, MT1-MMP, mt1-mmp, Mt1-mmp, MT1MMP, MTMMP1, mtmmp1, sabe, sb:cb386, wu:fb72b09

Protein level used designations for Matrix Metallopeptidase 14 (Membrane-inserted)

  • MMP-14
  • MT-MMP 1
  • MT1-MMP
  • MT1MMP
  • MTMMP1
  • matrix metallopeptidase 1 (interstitial collagenase)
  • matrix metalloproteinase 14
  • matrix metalloproteinase-14
  • membrane type 1 metalloproteinase
  • membrane-type matrix metalloproteinase 1
  • membrane-type-1 matrix metalloproteinase
  • membrane type 1 metalloprotease
  • matrix metalloproteinase 14 (membrane-inserted)
  • matrix metalloproteinase 14 preproprotein
  • membrane type-1 metalloproteinase
  • matric metalloproteinase 14
  • MMP-X1
  • Membrane type 1-MMP
  • type 1 matrix metalloprotease 14
  • matrix metalloproteinase 14 membrane-inserted
  • matrix metalloproteinase 14, membrane-inserted
  • membrane type 1-matrix metalloproteinase
  • membrane-type 1 matrix metalloproteinase
  • matrix metalloproteinase 14 (membrane-inserted) beta
  • matrix metalloproteinase 14b (membrane-inserted)
  • zMT-MMP-beta
  • MT-MMPalpha
  • matrix metalloproteinase 14 (membrane-inserted) alpha
  • matrix metalloproteinase 14a (membrane-inserted)
  • zMT-MMP-alpha
  • zMT-MMPalpha
  • matrix metallopeptidase 14 (membrane-inserted)
  • matrix metallopeptidase 14 L homeolog
  • membrane type-1 matrix metalloproteinase 14
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