MATK Products
(Megakaryocyte-Associated tyrosine Kinase (MATK))
Categories
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Featured MATK Categories
MATK Antibodies
High quality antibodies with extensive validation data.
MATK ELISA Kits
Reliable ELISA kits for a wide range of species.
MATK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MATK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7159178
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, ICC, IF
Validations
- (3)
Cat. No.
ABIN6259101
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (1)
- (2)
Cat. No.
ABIN969495
Quantity
100 μL
Datasheet
Datasheet
Recommended MATK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4886198
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5594938
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1141899
Quantity
96 tests
Datasheet
Datasheet
Recommended MATK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310443
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310445
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5509002
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MATK products
: "Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." in: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).: "Overexpression of the Csk homologous kinase facilitates phosphorylation of Akt/PKB in MCF-7 cells." in: International journal of oncology, Vol. 21, Issue 6, pp. 1347-52, (2002) (PubMed).
: "Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancer." in: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36465-70, (2002) (PubMed).
Synonyms and alternative names related to MATK
megakaryocyte-associated tyrosine kinase (matk), megakaryocyte-associated tyrosine kinase (MATK), megakaryocyte-associated tyrosine kinase (Matk), zinc finger RNA binding protein 2 (ZFR2), Batk, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk, Ntk, si:ch211-63j24.2Protein level used designations for MATK
- megakaryocyte-associated tyrosine kinase
- megakaryocyte-associated tyrosine-protein kinase-like
- CSK homologous kinase
- Csk-homologous kinase
- Csk-type protein tyrosine kinase
- HYL tyrosine kinase
- hematopoietic consensus tyrosine-lacking kinase
- hydroxyaryl-protein kinase
- leukocyte carboxyl-terminal src kinase related
- megakaryocyte-associated tyrosine-protein kinase
- protein kinase HYL
- tyrosine kinase MATK
- tyrosine-protein kinase CTK
- tyrosylprotein kinase
- Csk homologous kinase
- protein kinase NTK
- megakaryocyte-associated tyrosine kinase (non-receptor protein tyrosine kinase)
- non-receptor protein kinase protein
- protein kinase BATK
- carboxyl-terminal SRC kinase homologous kinase
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