MAT1A Products
(Methionine Adenosyltransferase I, alpha (MAT1A))
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This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008].
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Featured MAT1A Categories
MAT1A Antibodies
High quality antibodies with extensive validation data.
MAT1A ELISA Kits
Reliable ELISA kits for a wide range of species.
MAT1A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAT1A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
Cat. No.
ABIN517744
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6263141
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (2)
Cat. No.
ABIN656632
Quantity
400 μL
Datasheet
Datasheet
Recommended MAT1A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968589
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968588
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968587
Quantity
96 tests
Datasheet
Datasheet
Recommended MAT1A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123931
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310434
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310436
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MAT1A products
: "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice." in: Scientific reports, Vol. 10, Issue 1, pp. 14831, (2021) (PubMed).: "Unraveling the role of quorum sensing-dependent metabolic homeostasis of the activated methyl cycle in a cooperative population of Burkholderia glumae." in: Scientific reports, Vol. 9, Issue 1, pp. 11038, (2019) (PubMed).
: "DMBA acts on cumulus cells to desynchronize nuclear and cytoplasmic maturation of pig oocytes." in: Scientific reports, Vol. 7, Issue 1, pp. 1687, (2018) (PubMed).
: "Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap." in: Biology open, Vol. 4, Issue 9, pp. 1154-62, (2015) (PubMed).
: "Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells." in: The Journal of biological chemistry, Vol. 289, Issue 47, pp. 32639-55, (2014) (PubMed).
: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
: "Hepatic metabolite profiles in mice with a suboptimal selenium status." in: The Journal of nutritional biochemistry, Vol. 25, Issue 9, pp. 914-22, (2014) (PubMed).
: "Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma." in: Acta pharmacologica Sinica, Vol. 34, Issue 7, pp. 951-9, (2013) (PubMed).
: "MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma." in: The Journal of clinical investigation, Vol. 123, Issue 1, pp. 285-98, (2013) (PubMed).
: "Cyanidin-3-O-?-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells." in: Lipids in health and disease, Vol. 11, pp. 10, (2012) (PubMed).
Synonyms and alternative names related to MAT1A
methionine adenosyltransferase 1A (MAT1A), methionine adenosyltransferase 1A (Mat1a), methionine adenosyltransferase I, alpha (Mat1a), methionine adenosyltransferase I, alpha (mat1a), AdoMet, AI046368, Ams, MAT, MATA1, SADE, SAMS, SAMS1, SAS, wu:fi35e01, zgc:55442Protein level used designations for MAT1A
- MAT 1
- MAT-I/III
- S-adenosylmethionine synthase isoform type-1
- S-adenosylmethionine synthetase isoform type-1
- adoMet synthase 1
- adoMet synthetase 1
- methionine adenosyltransferase 1
- methionine adenosyltransferase I/III
- S - adenosylmethionine synthetase
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