MARK2 Products
(MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
Categories
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009].
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Featured MARK2 Categories
MARK2 Antibodies
High quality antibodies with extensive validation data.
MARK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MARK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (5)
Cat. No.
ABIN560734
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN392538
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, WB, IHC
Validations
- (5)
Cat. No.
ABIN3031689
Quantity
0.4 mL
Datasheet
Datasheet
Recommended MARK2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6219503
Quantity
96 tests
Datasheet
Datasheet
Recommended MARK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310392
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310391
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508999
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MARK2 products
: "Insulin Induces Microtubule Stabilization and Regulates the Microtubule Plus-end Tracking Protein Network in Adipocytes." in: Molecular & cellular proteomics : MCP, Vol. 18, Issue 7, pp. 1363-1381, (2019) (PubMed).: "Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein." in: Molecular & cellular proteomics : MCP, Vol. 16, Issue 10, pp. 1718-1735, (2017) (PubMed).
: "Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes." in: Aging cell, Vol. 11, Issue 1, pp. 51-62, (2012) (PubMed).
: "Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2414-25, (2008) (PubMed).
: "Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF." in: Histopathology, Vol. 52, Issue 4, pp. 500-9, (2008) (PubMed).
: "Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity." in: Current biology : CB, Vol. 14, Issue 8, pp. 736-41, (2004) (PubMed).
: "Splicing alterations in human renal allografts: detection of a new splice variant of protein kinase Par1/Emk1 whose expression is associated with an increase of inflammation in protocol biopsies of ..." in: Biochimica et biophysica acta, Vol. 1689, Issue 1, pp. 58-65, (2004) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling." in: Nature cell biology, Vol. 3, Issue 7, pp. 628-36, (2001) (PubMed).
Synonyms and alternative names related to MARK2
microtubule affinity regulating kinase 2 (MARK2), MAP/microtubule affinity regulating kinase 2 (Mark2), microtubule affinity regulating kinase 2 (Mark2), AU024026, Emk, EMK-1, EMK1, mKIAA4207, PAR-1, Par-1, Par-1b, Par1bProtein level used designations for MARK2
- ELKL motif kinase 1
- PAR1 homolog b
- Ser/Thr protein kinase PAR-1B
- serine/threonine protein kinase EMK
- serine/threonine-protein kinase MARK2
- EMK-1
- EMK1
- serine/threonine kinase
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