MARCO Products
(Macrophage Receptor with Collagenous Structure (MARCO))
Categories
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008].
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Featured MARCO Categories
MARCO Antibodies
High quality antibodies with extensive validation data.
MARCO ELISA Kits
Reliable ELISA kits for a wide range of species.
MARCO Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MARCO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IP, IHC, ICC
Validations
- (4)
Cat. No.
ABIN7444610
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (2)
- (3)
Cat. No.
ABIN653847
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7158886
Quantity
100 μL
Datasheet
Datasheet
Recommended MARCO ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730744
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1141381
Quantity
96 tests
Datasheet
Datasheet
Recommended MARCO Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275278
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275279
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418587
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MARCO products
: "Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes." in: The Journal of biological chemistry, Vol. 292, Issue 33, pp. 13615-13634, (2017) (PubMed).: "DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins." in: Medicine, Vol. 95, Issue 7, pp. e2853, (2016) (PubMed).
: "Phagosomal Acidification Prevents Macrophage Inflammatory Cytokine Production to Malaria, and Dendritic Cells Are the Major Source at the Early Stages of Infection: IMPLICATION FOR MALARIA PROTECTIVE ..." in: The Journal of biological chemistry, Vol. 290, Issue 38, pp. 23135-47, (2015) (PubMed).
: "The lung is protected from spontaneous inflammation by autophagy in myeloid cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5465-71, (2015) (PubMed).
: "Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains." in: Bioconjugate chemistry, Vol. 23, Issue 5, pp. 1003-9, (2014) (PubMed).
: "Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 9, pp. 4800-8, (2011) (PubMed).
: "MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 9, pp. 6058-64, (2005) (PubMed).
: "MARCO expression on pediatric alveolar macrophages." in: Cytometry. Part B, Clinical cytometry, Vol. 60, Issue 1, pp. 54-6, (2004) (PubMed).
: "Inducible expression of macrophage receptor Marco by dendritic cells following phagocytic uptake of dead cells uncovered by oligonucleotide arrays." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 6, pp. 2879-88, (2003) (PubMed).
: "Receptors for unopsonized particles: the role of alveolar macrophage scavenger receptors." in: Current molecular medicine, Vol. 1, Issue 5, pp. 589-95, (2002) (PubMed).
Synonyms and alternative names related to MARCO
macrophage receptor with collagenous structure (MARCO), macrophage receptor with collagenous structure (Marco), AI323439, Ly112, Scara2, SCARA2Protein level used designations for MARCO
- macrophage receptor MARCO
- scavenger receptor class A member 2
- scavenger receptor class A, member 2
- putative scavenger receptor MARCO
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