MARCH8 Products
(Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))
Categories
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]\; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010].
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Featured MARCH8 Categories
MARCH8 Antibodies
High quality antibodies with extensive validation data.
MARCH8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MARCH8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN566949
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6743175
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6743135
Quantity
100 μL
Datasheet
Datasheet
Recommended MARCH8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310377
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310379
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2725820
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our MARCH8 products
: "MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins." in: Nature medicine, Vol. 21, Issue 12, pp. 1502-7, (2015) (PubMed).: "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins." in: Journal of virology, Vol. 78, Issue 3, pp. 1109-20, (2004) (PubMed).
: "c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 14657-68, (2003) (PubMed).
Synonyms and alternative names related to MARCH8
membrane associated ring-CH-type finger 8 (MARCH8), membrane-associated ring finger (C3HC4) 8 (march8), membrane-associated ring finger (C3HC4) 8 (March8), membrane associated ring-CH-type finger 8 (March8), membrane associated ring-CH-type finger 8 (march8), membrane associated ring-CH-type finger 8 L homeolog (march8.L), 1300017E09Rik, c-MIR, Mar-08, MARCH-VIII, MARCH8, MIR, Mir, RNF178, zgc:171495Protein level used designations for MARCH8
- E3 ubiquitin-protein ligase MARCH8
- RING finger protein 178
- c-mir, cellular modulator of immune recognition
- cellular modulator of immune recognition (c-MIR)
- membrane-associated RING finger protein 8
- membrane-associated RING-CH protein VIII
- MARCH-VIII
- cellular modulator of immune recognition
- membrane-associated ring finger (C3HC4) 8
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