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MARCH2 Products

(Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

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MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]\; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010].

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Featured MARCH2 Categories

MARCH2 Antibodies

High quality antibodies with extensive validation data.

MARCH2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MARCH2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN949301
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN565570
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN526579
Quantity 50 μg
Datasheet Datasheet

Recommended MARCH2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310359
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310361
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2725492
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our MARCH2 products

Han, Xiao, Kim, Wu, Wisler, Nakamura, Freedman, Shenoy: "MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound ?(2)-adrenergic receptors." in: The Journal of cell biology, Vol. 199, Issue 5, pp. 817-30, (2012) (PubMed).

Wakisaka, Tsuda, Yamada, Yagihara, Kitamura: "Long-term results of saphenous vein graft for coronary stenosis caused by Kawasaki disease." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 73, Issue 1, pp. 73-7, (2008) (PubMed).

Nakamura, Fukuda, Kato, Hirose: "MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking." in: Molecular biology of the cell, Vol. 16, Issue 4, pp. 1696-710, (2005) (PubMed).

Synonyms and alternative names related to MARCH2

membrane associated ring-CH-type finger 2 (MARCH2), membrane associated ring-CH-type finger 2 S homeolog (march2.S), membrane associated ring-CH-type finger 2 (march2), E3 ubiquitin-protein ligase MARCH2 (Tsp_09446), E3 ubiquitin-protein ligase MARCH2 (marh2), membrane associated ring-CH-type finger 2 (March2), membrane-associated ring finger (C3HC4) 2 (March2), 9530046H09Rik, MARCH-II, marh2, rgd1306395, RGD1306395, RNF172

Protein level used designations for MARCH2

  • E3 ubiquitin-protein ligase MARCH2
  • RING finger protein 172
  • membrane-associated RING finger protein 2
  • membrane-associated RING-CH protein II
  • MARCH-II
  • membrane associated RING-CH finger protein II
  • syntaxin-6-binding protein
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