MAPKAP Kinase 5 Products
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
Categories
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012].
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Featured MAPKAP Kinase 5 Categories
MAPKAP Kinase 5 Antibodies
High quality antibodies with extensive validation data.
MAPKAP Kinase 5 ELISA Kits
Reliable ELISA kits for a wide range of species.
MAPKAP Kinase 5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAPKAP Kinase 5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN710546
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6255616
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN389587
Quantity
400 μL
Datasheet
Datasheet
Recommended MAPKAP Kinase 5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380844
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended MAPKAP Kinase 5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
Cat. No.
ABIN1310330
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310332
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317049
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our MAPKAP Kinase 5 products
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition." in: Toxicon : official journal of the International Society on Toxinology, Vol. 55, Issue 4, pp. 827-37, (2010) (PubMed).
: "Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs." in: Science signaling, Vol. 2, Issue 94, pp. ra69, (2009) (PubMed).
: "PRAK is essential for ras-induced senescence and tumor suppression." in: Cell, Vol. 128, Issue 2, pp. 295-308, (2007) (PubMed).
: "p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 97, Issue 8, pp. 629-40, (2005) (PubMed).
: "Effect of different dietary ideal protein concentrations on broiler performance." in: British poultry science, Vol. 45, Issue 4, pp. 504-11, (2004) (PubMed).
: "Regulation of PRAK subcellular location by p38 MAP kinases." in: Molecular biology of the cell, Vol. 14, Issue 6, pp. 2603-16, (2003) (PubMed).
: "p62 functions as a p38 MAP kinase regulator." in: Biochemical and biophysical research communications, Vol. 269, Issue 2, pp. 521-5, (2000) (PubMed).
Synonyms and alternative names related to MAPKAP Kinase 5
mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5), MAP kinase-activated protein kinase 5 (Mapkapk5), mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5), MAPKAP-K5, MAPKAPK5, MK-5, MK5, PRAKProtein level used designations for MAPKAP Kinase 5
- mitogen-activated protein kinase-activated protein kinase 5
- MAP kinase-activated protein kinase 5
- MAP kinase-activated protein kinase 5-like
- MAPK-activated protein kinase 5
- MAPKAP kinase 5
- MAPKAPK-5
- p38-regulated/activated protein kinase
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