MAPKAP Kinase 2 Products
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
Categories
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured MAPKAP Kinase 2 Categories
MAPKAP Kinase 2 Antibodies
High quality antibodies with extensive validation data.
MAPKAP Kinase 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
MAPKAP Kinase 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAPKAP Kinase 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441769
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IP, IF, PLA
Validations
- (8)
Cat. No.
ABIN563999
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN522742
Quantity
100 μg
Datasheet
Datasheet
Recommended MAPKAP Kinase 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968658
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380843
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380304
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended MAPKAP Kinase 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310322
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310324
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508995
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MAPKAP Kinase 2 products
: "Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway." in: PLoS pathogens, Vol. 13, Issue 3, pp. e1006266, (2017) (PubMed).: "P38 mitogen-activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture." in: Journal of cellular and molecular medicine, Vol. 17, Issue 4, pp. 508-17, (2013) (PubMed).
: "Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 12, pp. 1591-602, (2012) (PubMed).
: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." in: Transplantation, Vol. 85, Issue 3, pp. 398-406, (2008) (PubMed).
: "MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation." in: Molecular cell, Vol. 17, Issue 1, pp. 37-48, (2005) (PubMed).
: "Catalysis and function of the p38 alpha.MK2a signaling complex." in: Biochemistry, Vol. 43, Issue 31, pp. 9950-60, (2004) (PubMed).
: "Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2." in: Journal of cellular biochemistry, Vol. 89, Issue 3, pp. 589-602, (2003) (PubMed).
: "Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme." in: Structure (London, England : 1993), Vol. 11, Issue 6, pp. 627-36, (2003) (PubMed).
: "Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export." in: The Journal of biological chemistry, Vol. 277, Issue 40, pp. 37401-5, (2002) (PubMed).
: "Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48379-85, (2002) (PubMed).
Synonyms and alternative names related to MAPKAP Kinase 2
mitogen-activated protein kinase-activated protein kinase 2a (mapkapk2a), mitogen-activated protein kinase-activated protein kinase 2 L homeolog (mapkapk2.L), mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), MAP kinase-activated protein kinase 2 (Mapkapk2), mitogen-activated protein kinase-activated protein kinase 2 (Mapkapk2), AA960234, MAPKAP-K2, mapkapk2, MAPKAPK2, MGC78852, MK-2, MK2, Rps6kc1, wu:fb30e10, wu:fc56c10, wu:fi03a01Protein level used designations for MAPKAP Kinase 2
- MAP kinase-activated protein kinase 2
- bbp
- betty boop
- mitogen-activated protein kinase-activated protein kinase 2
- MAPK-activated protein kinase 2
- MAPKAP kinase 2
- MAPKAPK-2
- map kinase activated protein kinase-2
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