MAPK7 Products
(Mitogen-Activated Protein Kinase 7 (MAPK7))
Categories
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured MAPK7 Categories
MAPK7 Antibodies
High quality antibodies with extensive validation data.
MAPK7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAPK7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3022945
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7442186
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (5)
Cat. No.
ABIN3031834
Quantity
0.4 mL
Datasheet
Datasheet
Recommended MAPK7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6216856
Quantity
96 tests
Datasheet
Datasheet
Recommended MAPK7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310301
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310300
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508923
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MAPK7 products
: "CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5-AP-1 axis." in: Cell death & disease, Vol. 7, Issue 10, pp. e2415, (2017) (PubMed).: "A novel role of ERK5 in integrin-mediated cell adhesion and motility in cancer cells via Fak signaling." in: Journal of cellular physiology, Vol. 219, Issue 1, pp. 152-61, (2009) (PubMed).
: "Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells." in: Molecular and cellular biochemistry, Vol. 322, Issue 1-2, pp. 171-8, (2009) (PubMed).
: "Expression of Erk5 in early stage breast cancer and association with disease free survival identifies this kinase as a potential therapeutic target." in: PLoS ONE, Vol. 4, Issue 5, pp. e5565, (2009) (PubMed).
: "ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry." in: Genes, chromosomes & cancer, Vol. 48, Issue 2, pp. 109-20, (2008) (PubMed).
: "Erk5 controls Slug expression and keratinocyte activation during wound healing." in: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4738-49, (2008) (PubMed).
Synonyms and alternative names related to MAPK7
mitogen-activated protein kinase 7 (MAPK7), mitogen-activated protein kinase 7 (Mapk7), MAP kinase 7 (MPK7), mitogen-activated protein kinase 7 L homeolog (mapk7.L), ATMPK7, BMK1, Bmk1, bmk1, ERK-5, ERK4, erk4, ERK5, Erk5, Erk5-T, F8D23.5, F8D23_5, mapk7, MAP kinase 7, PRKM7, Prkm7, prkm7Protein level used designations for MAPK7
- BMK-1
- BMK1 kinase
- ERK-5
- MAP kinase 7
- MAPK 7
- big MAP kinase 1
- extracellular signal-regulated kinase 5
- extracellular-signal-regulated kinase 5
- extracellular signal regulated kinase 5
- mitogen activated protein kinase 7
- mitogen-activated kinase 7
- Big MAP kinase 1
- Extracellular signal-regulated kinase 5
- LOW QUALITY PROTEIN: mitogen-activated protein kinase 7
- ERK5
- bmk I
- mitogen-activated protein kinase 7 L homeolog
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