MAP4K2 Products
(Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))
Categories
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. [provided by RefSeq, Jul 2008].
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Featured MAP4K2 Categories
MAP4K2 Antibodies
High quality antibodies with extensive validation data.
MAP4K2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAP4K2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7160065
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6258837
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN391081
Quantity
400 μL
Datasheet
Datasheet
Recommended MAP4K2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228744
Quantity
96 tests
Datasheet
Datasheet
Recommended MAP4K2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310248
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317061
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505302
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MAP4K2 products
: "Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2." in: Molecular and cellular biology, Vol. 22, Issue 3, pp. 737-49, (2002) (PubMed).: "Cancer. A deadly inheritance." in: Nature, Vol. 348, Issue 6303, pp. 681-2, (1991) (PubMed).
: "p53 functions as a cell cycle control protein in osteosarcomas." in: Molecular and cellular biology, Vol. 10, Issue 11, pp. 5772-81, (1990) (PubMed).
Synonyms and alternative names related to MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2), mitogen-activated protein kinase kinase kinase kinase 2 (Map4k2), mitogen activated protein kinase kinase kinase kinase 2 (Map4k2), mitogen-activated protein kinase kinase kinase kinase 2 (LOC103346779), mitogen-activated protein kinase kinase kinase kinase 2 (map4k2), AI385662, BL44, dZ150L22.2, GCK, MAP4K2, map4k2l, map4k2l-2, map4k3l, RAB8IP, Rab8ip, si:dz150l22.2, si:dz263j20.1, zgc:136670Protein level used designations for MAP4K2
- B lymphocyte serine/threonine protein kinase
- MAPK/ERK kinase kinase kinase 2
- MEK kinase kinase 2
- MEKKK 2
- Rab8 interacting protein
- germinal centre kinase (GC kinase)
- RAB8 interacting protein
- germinal center kinase
- mitogen activated protein kinase kinase kinase kinase 2
- rab8-interacting protein
- mitogen-activated protein kinase kinase kinase kinase 2
- mitogen-activated protein kinase kinase kinase kinase 2-like
- mitogen-activated protein kinase kinase kinase kinase 3-like
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