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MAP3K2 Products

(Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Categories

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008].

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Featured MAP3K2 Categories

MAP3K2 Antibodies

High quality antibodies with extensive validation data.

MAP3K2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAP3K2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, ICC
Validations
  • (2)
  • (4)
Cat. No. ABIN969272
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN657838
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7160033
Quantity 100 μL
Datasheet Datasheet

Recommended MAP3K2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6219421
Quantity 96 tests
Datasheet Datasheet

Recommended MAP3K2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310212
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509008
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3083472
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MAP3K2 products

Li, Zhang, Zhou, Li, Liu, Wang, Bai, Zhao, Shi, Zhang, Ye: "The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling." in: Cancer letters, Vol. 355, Issue 2, pp. 288-96, (2014) (PubMed).

Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).

Cazares, Troyer, Mendrinos, Lance, Nyalwidhe, Beydoun, Clements, Drake, Semmes: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).

Gollob, Sciambi, Huang, Dressman: "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." in: Cancer research, Vol. 65, Issue 19, pp. 8869-77, (2005) (PubMed).

Synonyms and alternative names related to MAP3K2

mitogen activated protein kinase kinase kinase 2 (Map3k2), mitogen-activated protein kinase kinase kinase 2 (MAP3K2), mitogen-activated protein kinase kinase kinase 2 (Map3k2), 9630061B06Rik, AI585793, Mekk2, MEKK2, MEKK2B, Mekk2b

Protein level used designations for MAP3K2

  • mitogen-activated protein kinase kinase kinase 2
  • MAP/ERK kinase kinase 2
  • MAPK/ERK kinase kinase 2
  • MEK kinase 2
  • MEKK 2
  • mitogen activated protein kinase kinase kinase 2
  • protein kinase MEKK2b
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