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MAP3K14 Products

(Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Categories

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008].

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Featured MAP3K14 Categories

MAP3K14 Antibodies

High quality antibodies with extensive validation data.

MAP3K14 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAP3K14 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN7193410
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN724520
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, PLA
Validations
  • (3)
Cat. No. ABIN522453
Quantity 100 μg
Datasheet Datasheet

Recommended MAP3K14 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124003
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310208
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310206
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MAP3K14 products

Guo, Chang, Liu, Li, Huang, Ann, Wang, Lin, Wu, Yuan, Yen: "Canonical nuclear factor ?B pathway links tumorigenesis of synchronous mantle-cell lymphoma, clear-cell renal-cell carcinoma, and GI stromal tumor." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 29, Issue 10, pp. e257-61, (2011) (PubMed).

Perreault, Bergman, Hunerdosse, Playdon, Eckel: "Inflexibility in intramuscular triglyceride fractional synthesis distinguishes prediabetes from obesity in humans." in: Obesity (Silver Spring, Md.), Vol. 18, Issue 8, pp. 1524-31, (2010) (PubMed).

Austin, Rune, Bouzakri, Zierath, Krook: "siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle." in: Diabetes, Vol. 57, Issue 8, pp. 2066-73, (2008) (PubMed).

Bouzakri, Zierath: "MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 7783-9, (2007) (PubMed).

Andreakos, Smith, Monaco, Brennan, Foxwell, Feldmann: "Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction." in: Blood, Vol. 101, Issue 3, pp. 983-91, (2003) (PubMed).

Ponath, Qin, Ringler, Clark-Lewis, Wang, Kassam, Smith, Shi, Gonzalo, Newman, Gutierrez-Ramos, Mackay: "Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils." in: The Journal of clinical investigation, Vol. 97, Issue 3, pp. 604-12, (1996) (PubMed).

Synonyms and alternative names related to MAP3K14

mitogen-activated protein kinase kinase kinase 14 (MAP3K14), mitogen-activated protein kinase kinase kinase 14 (Map3k14), mitogen-activated protein kinase kinase kinase 14 (MAPKKK14), aly, F23F1.4, F23F1_4, FTDCR1B, HS, HSNIK, mitogen-activated protein kinase kinase kinase 14, NIK, Nik

Protein level used designations for MAP3K14

  • NF-kappa-beta-inducing kinase
  • serine/threonine protein-kinase
  • serine/threonine-protein kinase NIK
  • NF kappa B-inducing kinase
  • Nfkb inducing kinase
  • alymphoplasia
  • protein kinase
  • mitogen-activated protein kinase kinase kinase 14
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