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MAP3K1 Products

(Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012].

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Featured MAP3K1 Categories

MAP3K1 Antibodies

High quality antibodies with extensive validation data.

MAP3K1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MAP3K1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAP3K1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7442936
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6256476
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (3)
Cat. No. ABIN561796
Quantity 100 μg
Datasheet Datasheet

Recommended MAP3K1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1142947
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142948
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1142949
Quantity 96 tests
Datasheet Datasheet

Recommended MAP3K1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310194
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509007
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415728
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MAP3K1 products

Craig, Parker, Austin, Barnett, Camenisch: "Involvement of the MEKK1 signaling pathway in the regulation of epicardial cell behavior by hyaluronan." in: Cellular signalling, Vol. 22, Issue 6, pp. 968-76, (2010) (PubMed).

Mokhtari, Myers, Welsh: "MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells." in: Diabetes, Vol. 57, Issue 7, pp. 1896-904, (2008) (PubMed).

Synonyms and alternative names related to MAP3K1

mitogen-activated protein kinase kinase kinase 1 (MAP3K1), mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (map3k1), mitogen-activated protein kinase kinase kinase 1 (map3k1), mitogen-activated protein kinase kinase kinase 1 (Map3k1), MAPK/ERK kinase kinase 1 (MEKK1), mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (MAP3K1), ARAKIN, ATMEKK1, MAP3K1, MAPK/ERK kinase kinase 1, MAPKKK1, MAPKKK8, Mekk, MEKK, Mekk1, MEKK1, MEKK 1, SRXY6, T15F16.5, T15F16_5

Protein level used designations for MAP3K1

  • mitogen-activated protein kinase kinase kinase 1
  • MAPK/ERK kinase kinase 1
  • MEK kinase 1
  • MEKK 1
  • mitogen activated protein kinase kinase kinase 1
  • MAP/ERK kinase kinase 1
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