MAP2K6 Products
(Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
Categories
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008].
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Featured MAP2K6 Categories
MAP2K6 Antibodies
High quality antibodies with extensive validation data.
MAP2K6 ELISA Kits
Reliable ELISA kits for a wide range of species.
MAP2K6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAP2K6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (7)
Cat. No.
ABIN7443209
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN969269
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN969270
Quantity
100 μL
Datasheet
Datasheet
Recommended MAP2K6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Semi-Quantitative Cell ELISA
Validations
Cat. No.
ABIN4881293
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380643
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN2748365
Quantity
96 tests
Datasheet
Datasheet
Recommended MAP2K6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124002
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310187
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310189
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our MAP2K6 products
: "MAPK kinase 10.2 promotes disease resistance and drought tolerance by activating different MAPKs in rice." in: The Plant journal : for cell and molecular biology, Vol. 92, Issue 4, pp. 557-570, (2018) (PubMed).: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).
: "Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice." in: Biological trace element research, Vol. 173, Issue 2, pp. 333-8, (2016) (PubMed).
: "ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 4, pp. 485-90, (2008) (PubMed).
: "The MEK/ERK cascade: from signaling specificity to diverse functions." in: Biochimica et biophysica acta, Vol. 1773, Issue 8, pp. 1213-26, (2007) (PubMed).
: "Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction." in: Oncogene, Vol. 23, Issue 10, pp. 1845-53, (2004) (PubMed).
: "Apoptosis signaling triggered by the marine alkaloid ascididemin is routed via caspase-2 and JNK to mitochondria." in: Oncogene, Vol. 23, Issue 8, pp. 1586-93, (2004) (PubMed).
: "Tobacco smoke control of mucin production in lung cells requires oxygen radicals AP-1 and JNK." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39085-93, (2004) (PubMed).
: "p38 Mitogen-activated protein kinase-dependent and -independent signaling of mRNA stability of AU-rich element-containing transcripts." in: Molecular and cellular biology, Vol. 23, Issue 2, pp. 425-36, (2003) (PubMed).
: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, (2002) (PubMed).
Synonyms and alternative names related to MAP2K6
mitogen-activated protein kinase kinase 6 (MAP2K6), mitogen-activated protein kinase kinase 6 (Map2k6), mitogen-activated protein kinase kinase 6 (map2k6), mitogen-activated protein kinase kinase 6 L homeolog (map2k6.L), map2k3, map2k6, MAPKK6, MEK6, MKK3, MKK6, Mkk6, PRKMK6, Prkmk6, SAPKK-3, SAPKK3, zMKK3Protein level used designations for MAP2K6
- MAPK/ERK kinase 6
- MAPKK 6
- MEK 6
- SAPK kinase 3
- dual specificity mitogen-activated protein kinase kinase 6
- protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
- stress-activated protein kinase kinase 3
- MAP kinase kinase 6
- mitogen activated protein kinase kinase 6
- protein kinase, mitogen activated, kinase 6
- mitogen-activated protein kinase kinase 3
- mitogen-activated protein kinase kinase 6 L homeolog
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