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Manic Fringe Products

(MFNG)

Categories

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009].

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Featured Manic Fringe Categories

Manic Fringe Antibodies

High quality antibodies with extensive validation data.

Manic Fringe ELISA Kits

Reliable ELISA kits for a wide range of species.

Manic Fringe Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Manic Fringe Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF
Validations
  • (2)
Cat. No. ABIN6258883
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN561813
Quantity 50 μL
Datasheet Datasheet
Reactivity Bat, Dog, Guinea Pig, Horse, Human, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6752975
Quantity 100 μL
Datasheet Datasheet

Recommended Manic Fringe ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1742786
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1773690
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1750115
Quantity 96 tests
Datasheet Datasheet

Recommended Manic Fringe Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310807
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310809
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405394
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Manic Fringe products

Bray: "Notch signalling: a simple pathway becomes complex." in: Nature reviews. Molecular cell biology, Vol. 7, Issue 9, pp. 678-89, (2006) (PubMed).

Synonyms and alternative names related to Manic Fringe

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Mfng), AW546563

Protein level used designations for Manic Fringe

  • O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • beta-1,3-N-acetylglucosaminyltransferase manic fringe
  • manic fringe homolog
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