MAN1B1 Products
(Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1))
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This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011].
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Featured MAN1B1 Categories
MAN1B1 Antibodies
High quality antibodies with extensive validation data.
MAN1B1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MAN1B1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (6)
Cat. No.
ABIN564895
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IF
Validations
- (3)
Cat. No.
ABIN6263089
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7187242
Quantity
100 μg
Datasheet
Datasheet
Recommended MAN1B1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1310131
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN4370760
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318446
Quantity
50 μg
Datasheet
Datasheet
Synonyms and alternative names related to MAN1B1
mannosidase alpha class 1B member 1 (MAN1B1), mannosidase, alpha, class 1B, member 1 L homeolog (man1b1.L), endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (LOC480667), mannosidase, alpha, class 1B, member 1 (man1b1), mannosidase, alpha, class 1B, member 1 (Man1b1), E430019H13Rik, erman1, ERMAN1, ERMan1, Gm108, MAN1B1, mana-er, MANA-ER, MRT15, RGD1563595Protein level used designations for MAN1B1
- mannosidase, alpha, class 1B, member 1
- alpha 1,2-mannosidase
- ER alpha 1,2-mannosidase
- Man9GlcNAc2-specific processing alpha-mannosidase
- endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
- endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1
- ER alpha-1,2-mannosidase
- ER mannosidase 1
- man9GlcNAc2-specific-processing alpha-mannosidase
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