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MAGE-Like 2 Products

(MAGE-Like 2 (MAGEL2))

Categories

Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010].

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Featured MAGE-Like 2 Categories

MAGE-Like 2 Antibodies

High quality antibodies with extensive validation data.

MAGE-Like 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAGE-Like 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN390122
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7191360
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Monkey, Pig, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6746703
Quantity 100 μL
Datasheet Datasheet

Recommended MAGE-Like 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093669
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137400
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MAGE-Like 2 products

Boccaccio, Glatt-Deeley, Watrin, Roëckel, Lalande, Muscatelli: "The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region." in: Human molecular genetics, Vol. 8, Issue 13, pp. 2497-505, (2000) (PubMed).

Lee, Kozlov, Hernandez, Chamberlain, Brannan, Stewart, Wevrick: "Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype." in: Human molecular genetics, Vol. 9, Issue 12, pp. 1813-9, (2000) (PubMed).

Synonyms and alternative names related to MAGE-Like 2

MAGE family member L2 (MAGEL2), melanoma antigen, family L, 2 (Magel2), MAGE family member L2 (Magel2), Mage-l2, MAGEL2, NDNL1, nM15, ns7

Protein level used designations for MAGE-Like 2

  • MAGE-like protein 2
  • necdin-like protein 1
  • protein nM15
  • MAGE-like 2
  • melanoma antigen-like gene 2
  • necdin-like 1
  • protein nS7
  • melanoma antigen, family L, 2
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