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Macrophage Scavenger Receptor 1 Products

(Macrophage Scavenger Receptor 1 (MSR1))
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008].

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Featured Macrophage Scavenger Receptor 1 Categories

Macrophage Scavenger Receptor 1 Antibodies

High quality antibodies with extensive validation data.

Macrophage Scavenger Receptor 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Macrophage Scavenger Receptor 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Macrophage Scavenger Receptor 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Sheep
Application WB, ELISA, FACS, IHC (fro), IF (cc), IF (p), IHC (p)
Validations
  • (5)
Cat. No. ABIN872905
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (5)
Cat. No. ABIN7193254
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6263400
Quantity 100 μL
Datasheet Datasheet

Recommended Macrophage Scavenger Receptor 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6957614
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968418
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973534
Quantity 96 tests
Datasheet Datasheet

Recommended Macrophage Scavenger Receptor 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275296
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311469
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN5854557
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Macrophage Scavenger Receptor 1 products

Qian, Jiao, Wang, Liu, Cao, Yang: "Mechanism of TGF-β1 inhibiting Kupffer cell immune responses in cholestatic cirrhosis." in: Experimental and therapeutic medicine, Vol. 20, Issue 2, pp. 1541-1549, (2020) (PubMed).

Kamata, So, Ahmed, Giblett, Patel, Luo, Reddel, Pritchard: "Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development." in: Cell reports, Vol. 31, Issue 12, pp. 107802, (2020) (PubMed).

Hu, Jiang, Guo, Li, Chen, Zhang, Du, Wang, Zheng, Fang, Li, Song, Xie, Huang, Xue, Bai, Jia, Liu, Ren, Zhang, Guo, Pan, Su, Yi, Ye, Zuo, Li, Wu, Wang, Li, Liu, Wang, Li: "Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study." in: Nature communications, Vol. 11, Issue 1, pp. 1911, (2020) (PubMed).

Luong, Chino, Oyama, Matsushita, Sasaki, Ogura, Niwa, Biswas, Hamasaki, Fujita, Okamoto, Otsuka, Ihn, Hasegawa: "Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis." in: Arthritis research & therapy, Vol. 20, Issue 1, pp. 46, (2018) (PubMed).

Kwak, Jang, Lee, Jung, Kim, Kim, Kim, Kang: "Effect of Orally Administered Atractylodes macrocephala Koidz Water Extract on Macrophage and T Cell Inflammatory Response in Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 4041873, (2018) (PubMed).

Hamon, Tran, Roscioli, Ween, Jersmann, Hodge: "Bushfire smoke is pro-inflammatory and suppresses macrophage phagocytic function." in: Scientific reports, Vol. 8, Issue 1, pp. 13424, (2018) (PubMed).

Komai, Shichita, Ito, Kanamori, Chikuma, Yoshimura: "Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation." in: International immunology, Vol. 29, Issue 2, pp. 59-70, (2017) (PubMed).

Bellora, Dondero, Corrias, Casu, Regis, Caliendo, Moretta, Cazzola, Elena, Vinti, Locatelli, Bottino, Castriconi: "Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1516-1525, (2017) (PubMed).

Ween, Whittall, Hamon, Reynolds, Hodge: "Phagocytosis and Inflammation: Exploring the effects of the components of E-cigarette vapor on macrophages." in: Physiological reports, Vol. 5, Issue 16, (2017) (PubMed).

Zhang, Cao, He, Liu, Zhang, Yang, Du, Xu, Hu, Gao: "Combination of plasma HA and circulating M2-like monocytes may serve as a diagnostic marker for breast cancer." in: Journal of Cancer, Vol. 8, Issue 17, pp. 3522-3530, (2017) (PubMed).

Synonyms and alternative names related to Macrophage Scavenger Receptor 1

macrophage scavenger receptor 1 (MSR1), macrophage scavenger receptor 1 (Msr1), scavenger receptor class A member 5 (SCARA5), CD204, MRS-A, MSR, MSR-A, MSR1, phSR1, phSR2, RGD1564316, SCARA1, Scara1, Scvr, SR-A, SR-AI, SR-AII, SRA

Protein level used designations for Macrophage Scavenger Receptor 1

  • macrophage acetylated LDL receptor I and II
  • macrophage scavenger receptor type III
  • macrophage scavenger receptor types I and II
  • scavenger receptor class A member 1
  • scavenger receptor class A, member 1
  • SR-A
  • scavenger receptor type A
  • macrophage scavenger receptor 1
  • macrophage scavenger receptor type I
  • macrophage scavenger receptor types I and II-like
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