MACC1 Products
(Metastasis Associated in Colon Cancer 1 (MACC1))
Categories
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009].
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Featured MACC1 Categories
MACC1 Antibodies
High quality antibodies with extensive validation data.
MACC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MACC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended MACC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (6)
- (5)
Cat. No.
ABIN706526
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7159558
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1859735
Quantity
100 μL
Datasheet
Datasheet
Recommended MACC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6957784
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975740
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5656849
Quantity
96 tests
Datasheet
Datasheet
Recommended MACC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7386299
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093653
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3010685
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our MACC1 products
: "MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." in: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).
: "A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway." in: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 76, (2016) (PubMed).
: "Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 3423-31, (2015) (PubMed).
: "Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer." in: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 1094-100, (2015) (PubMed).
: "Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study." in: BMC cancer, Vol. 15, pp. 160, (2015) (PubMed).
: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." in: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).
: "Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression." in: International journal of cancer, Vol. 135, Issue 3, pp. 563-73, (2014) (PubMed).
: "Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis." in: Neuro-oncology, Vol. 15, Issue 12, pp. 1696-709, (2013) (PubMed).
: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." in: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).
Synonyms and alternative names related to MACC1
MACC1, MET transcriptional regulator (MACC1), metastasis associated in colon cancer 1 (Macc1), MACC1, MET transcriptional regulator (Macc1), 7A5, 7a5, 4732474O15Rik, Gm267, RGD1309838, SH3BP4LProtein level used designations for MACC1
- SH3 domain-containing protein 7a5
- metastasis-associated in colon cancer protein 1
- putative binding protein 7a5
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