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LYN Products

(V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

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This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].

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Featured LYN Categories

LYN Antibodies

High quality antibodies with extensive validation data.

LYN ELISA Kits

Reliable ELISA kits for a wide range of species.

LYN Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LYN Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (8)
Cat. No. ABIN6256754
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6263031
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN392102
Quantity 400 μL
Datasheet Datasheet

Recommended LYN ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960426
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380125
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886186
Quantity 96 tests
Datasheet Datasheet

Recommended LYN Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125686
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309923
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309925
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our LYN products

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Iriyama, Yuan, Hatta, Takagi, Takei et al.: "Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and ..." in: Cancer cell international, Vol. 16, pp. 37, (2016) (PubMed).

Hu, Takano, Xiang, Gilkes, Luo, Semenza: "Hypoxia-inducible factors enhance glutamate signaling in cancer cells." in: Oncotarget, Vol. 5, Issue 19, pp. 8853-68, (2014) (PubMed).

Kiflemariam, Andersson, Asplund, Pontén, Sjöblom: "Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers." in: PLoS ONE, Vol. 7, Issue 3, pp. e32927, (2012) (PubMed).

Queval, Nicolas, Beau: "Role of Src kinases in mobilization of glycosylphosphatidylinositol-anchored decay-accelerating factor by Dr fimbria-positive adhering bacteria." in: Infection and immunity, Vol. 79, Issue 7, pp. 2519-34, (2011) (PubMed).

Okamoto, Hayakawa, Miyata, Watamoto, Emi, Abe, Kiyoi, Towatari, Naoe: "Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD." in: Leukemia, Vol. 21, Issue 3, pp. 403-10, (2007) (PubMed).

Baran, Tridandapani, Helgason, Humphries, Krystal, Marsh: "The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38628-36, (2003) (PubMed).

Donato, Wu, Stapley, Gallick, Lin, Arlinghaus, Talpaz: "BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571." in: Blood, Vol. 101, Issue 2, pp. 690-8, (2003) (PubMed).

Liang, Wisniewski, Strife, Shivakrupa, Clarkson, Resh: "Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13732-8, (2002) (PubMed).

Santini, Scappini, Grossi, Gozzini, Bonsi, Pagliai, Rossi Ferrini, Bagnara: "Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647." in: Haematologica, Vol. 87, Issue 12, pp. 1242-7, (2002) (PubMed).

Synonyms and alternative names related to LYN

LYN proto-oncogene, Src family tyrosine kinase (LYN), v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (lyn), LYN proto-oncogene, Src family tyrosine kinase (Lyn), tyrosine-protein kinase Lyn (LOC100593961), LYN proto-oncogene, Src family tyrosine kinase L homeolog (lyn.L), LYN proto-oncogene, Src family tyrosine kinase (lyn), AA407514, CH73-38P6.3, Hck-2, JTK8, jtk8, lyn, LYN, lyn-A, p53Lyn, p56Lyn, zgc:92124

Protein level used designations for LYN

  • lck/Yes-related novel protein tyrosine kinase
  • tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Lyn
  • lyn protein tyrosine kinase
  • lyn protein non-receptor kinase
  • v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  • v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein
  • V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  • Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
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