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LY96 Products

(Lymphocyte Antigen 96 (LY96))

Categories

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010].

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Featured LY96 Categories

LY96 Antibodies

High quality antibodies with extensive validation data.

LY96 ELISA Kits

Reliable ELISA kits for a wide range of species.

LY96 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LY96 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7437365
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7436531
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN2565675
Quantity 50 μg
Datasheet Datasheet

Recommended LY96 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957561
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2703322
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6384779
Quantity 96 tests
Datasheet Datasheet

Recommended LY96 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309917
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320047
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2725664
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our LY96 products

Harada, Zhang, Imari, Yamasaki, Ni, Wu, Yamamoto, Kira, Nakanishi, Hayashi: "Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis." in: Pain, Vol. 160, Issue 9, pp. 2050-2062, (2019) (PubMed).

Xiong, Liu, Mei, Peng, Wang, Kong, Zhong, Xiong, Quan, Li, Wang, Huang: "Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling." in: Scientific reports, Vol. 7, pp. 41857, (2017) (PubMed).

Ellison, Gearheart, Porter, Ambruso: "IFN-γ alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils." in: PLoS ONE, Vol. 12, Issue 10, pp. e0185956, (2017) (PubMed).

Yang, Wang, Ju, Ragab, Lundbäck, Long, Valdes-Ferrer, He, Pribis, Li, Lu, Gero, Szabo, Antoine, Harris, Golenbock, Meng, Roth, Chavan, Andersson, Billiar, Tracey, Al-Abed: "MD-2 is required for disulfide HMGB1-dependent TLR4 signaling." in: The Journal of experimental medicine, Vol. 212, Issue 1, pp. 5-14, (2015) (PubMed).

Martin, Cabán-Hernández, Figueroa-Santiago, Espino: "Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3924-36, (2015) (PubMed).

Dulay, Buhimschi, Zhao, Oliver, Abdel-Razeq, Shook, Bahtiyar, Buhimschi: "Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 6, pp. 507-21, (2015) (PubMed).

Kunda, Cavicchia, Acosta: "Lipopolysaccharides and trophic factors regulate the LPS receptor complex in nodose and trigeminal neurons." in: Neuroscience, Vol. 280, pp. 60-72, (2014) (PubMed).

Liu, Yan, Liu, Wang, Li, Deng, Singh, Coleman, Rodgers: "Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 24, pp. 11056-61, (2010) (PubMed).

Tissières, Dunn-Siegrist, Schäppi, Elson, Comte, Nobre, Pugin: "Soluble MD-2 is an acute-phase protein and an opsonin for Gram-negative bacteria." in: Blood, Vol. 111, Issue 4, pp. 2122-31, (2008) (PubMed).

Daubeuf, Mathison, Spiller, Hugues, Herren, Ferlin, Kosco-Vilbois, Wagner, Kirschning, Ulevitch, Elson: "TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 9, pp. 6107-14, (2007) (PubMed).

Synonyms and alternative names related to LY96

lymphocyte antigen 96 (LY96), lymphocyte antigen 96 (Ly96), ESOP-1, ly-96, Ly-96, MD-2, MD2, Md2

Protein level used designations for LY96

  • myeloid differentiation protein-2
  • protein MD-2
  • ly-96
  • myeloid differentiation factor-2
  • LPS co-receptor MD-2
  • lymphocyte antigen 96
  • MD-2
  • Protein MD-2
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