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LSP1 Products

(Lymphocyte-Specific Protein 1 (LSP1))

Categories

This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured LSP1 Categories

LSP1 Antibodies

High quality antibodies with extensive validation data.

LSP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

LSP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LSP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN651634
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IHC (p), StM
Validations
  • (4)
Cat. No. ABIN6939969
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7268319
Quantity 100 μL
Datasheet Datasheet

Recommended LSP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951468
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1141104
Quantity 96 tests
Datasheet Datasheet

Recommended LSP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309855
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418305
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418197
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LSP1 products

Johansson, Tabor, Wikell, Jalkanen, Fuxe: "TGF-β1-Induced Epithelial-Mesenchymal Transition Promotes Monocyte/Macrophage Properties in Breast Cancer Cells." in: Frontiers in oncology, Vol. 5, pp. 3, (2015) (PubMed).

Koral, Paranjpe, Bowen, Mars, Luo, Michalopoulos: "Leukocyte-specific protein 1: a novel regulator of hepatocellular proliferation and migration deleted in human hepatocellular carcinoma." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 2, pp. 537-47, (2015) (PubMed).

Gringhuis, Kaptein, Wevers, Mesman, Geijtenbeek: "Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKK?- and CYLD-dependent Bcl3 activation." in: Nature communications, Vol. 5, pp. 3898, (2014) (PubMed).

Gringhuis, den Dunnen, Litjens, van der Vlist, Geijtenbeek: "Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori." in: Nature immunology, Vol. 10, Issue 10, pp. 1081-8, (2009) (PubMed).

Liu, Cara, Kaur, Raharjo, Mullaly, Jongstra-Bilen, Jongstra, Kubes: "LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration." in: The Journal of experimental medicine, Vol. 201, Issue 3, pp. 409-18, (2005) (PubMed).

Matsumoto, Kojima, Osawa, Toyoshima: "Protein kinase C phosphorylates p50 LSP1 and induces translocation of p50 LSP1 in T lymphocytes." in: Journal of biochemistry, Vol. 117, Issue 1, pp. 222-9, (1995) (PubMed).

Howard, Li, Torres, Guerrero, Coates: "The 47-kD protein increased in neutrophil actin dysfunction with 47- and 89-kD protein abnormalities is lymphocyte-specific protein." in: Blood, Vol. 83, Issue 1, pp. 231-41, (1994) (PubMed).

Kadiyala, McIntyre, Krensky: "Molecular cloning and characterization of WP34, a phosphorylated human lymphocyte differentiation and activation antigen." in: European journal of immunology, Vol. 20, Issue 11, pp. 2417-23, (1991) (PubMed).

Jongstra-Bilen, Young, Chong, Jongstra: "Human and mouse LSP1 genes code for highly conserved phosphoproteins." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 3, pp. 1104-10, (1990) (PubMed).

Klein, Jongstra-Bilen, Ogryzlo, Chong, Jongstra: "Lymphocyte-specific Ca2+-binding protein LSP1 is associated with the cytoplasmic face of the plasma membrane." in: Molecular and cellular biology, Vol. 9, Issue 7, pp. 3043-8, (1989) (PubMed).

Synonyms and alternative names related to LSP1

lymphocyte-specific protein 1 (LSP1), lymphocyte-specific protein 1 L homeolog (lsp1.L), lymphocyte specific 1 (Lsp1), lymphocyte-specific protein 1 (Lsp1), Lsp-1, LSP1, p50, pp52, WP34

Protein level used designations for LSP1

  • lymphocyte-specific protein 1
  • lymphocyte-specific protein 1, isoform 3
  • 52 kDa phosphoprotein
  • S37 protein
  • leukocyte specific protein 1
  • leukocyte-specific protein 1
  • lymphocyte-specific antigen WP34
  • 47 kDa actin binding protein
  • 47 kDa actin-binding protein
  • F-actin binding and cytoskeleton associated protein
  • leufactin (leukocyte F-actin binding protein)
  • 1 BAC CH230-300K22 (Children's Hospital Oakland Research Institute) complete
  • lymphocyte specific 1
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