LRRFIP1 Products
(Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1))
Categories
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
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Featured LRRFIP1 Categories
LRRFIP1 Antibodies
High quality antibodies with extensive validation data.
LRRFIP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LRRFIP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LRRFIP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN563976
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN465979
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN522657
Quantity
100 μg
Datasheet
Datasheet
Recommended LRRFIP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957447
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5656391
Quantity
96 tests
Datasheet
Datasheet
Recommended LRRFIP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309802
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309804
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7400858
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LRRFIP1 products
: "The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway." in: Nature immunology, Vol. 11, Issue 6, pp. 487-94, (2010) (PubMed).: "GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury." in: Circulation research, Vol. 84, Issue 11, pp. 1258-67, (1999) (PubMed).
: "Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor." in: The Journal of biological chemistry, Vol. 273, Issue 34, pp. 21594-602, (1998) (PubMed).
: "TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I." in: Nucleic acids research, Vol. 26, Issue 15, pp. 3460-7, (1998) (PubMed).
Synonyms and alternative names related to LRRFIP1
leucine rich repeat (in FLII) interacting protein 1a (lrrfip1a), LRR binding FLII interacting protein 1 (LRRFIP1), leucine rich repeat (in FLII) interacting protein 1 (Lrrfip1), LRR binding FLII interacting protein 1 (Lrrfip1), AU024550, FLAP-1, FLAP1, Fliiap1, FLIIAP1, GCF-2, GCF2, hm:zeh1367, HUFI-1, lrrfip1, LRRFIP1, TRIP, wu:fc06b04, wu:fi15c07, zeh1367Protein level used designations for LRRFIP1
- leucine rich repeat (in FLII) interacting protein 1
- leucine-rich repeat flightless-interacting protein 1-like
- FLAP (FLI LRR associated protein)
- FLI-LRR-associated protein 1
- H186 FLAP
- LRR FLII-interacting protein 1
- flap-1
- leucine-rich repeat flightless-interacting protein 1
- GC-binding factor 2
- NEDD8-conjugating enzyme
- TAR RNA-interacting protein
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