LRRC8A Products
(Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured LRRC8A Categories
LRRC8A Antibodies
High quality antibodies with extensive validation data.
LRRC8A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LRRC8A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
- (2)
Cat. No.
ABIN1881512
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, FACS, IF
Validations
- (4)
Cat. No.
ABIN7043301
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN1327159
Quantity
100 μg
Datasheet
Datasheet
Recommended LRRC8A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309795
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3116341
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136050
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our LRRC8A products
: "LRRC8 extracellular domain is composed of 17 leucine-rich repeats." in: Molecular immunology, Vol. 41, Issue 5, pp. 561-2, (2004) (PubMed).: "Genes required for B cell development." in: The Journal of clinical investigation, Vol. 112, Issue 11, pp. 1636-8, (2003) (PubMed).
Synonyms and alternative names related to LRRC8A
leucine rich repeat containing 8 VRAC subunit A (LRRC8A), leucine rich repeat containing 8A (Lrrc8a), leucine rich repeat containing 8 VRAC subunit A (Lrrc8a), leucine rich repeat containing 8 VRAC subunit Aa (lrrc8aa), leucine-rich repeat containing 8 family member A S homeolog (lrrc8a.S), leucine rich repeat containing 8 family member A (LRRC8A), AGM5, LLRC8A, LRRC8, Lrrc8, mKIAA1437, wu:fb18g12, wu:fi21b10Protein level used designations for LRRC8A
- leucine-rich repeat-containing protein 8A
- leucine-rich repeat-containing 8
- leucine rich repeat containing 8A
- leucine rich repeat containing 8 family member A
- volume-regulated anion channel subunit LRRC8A
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