LRP8 Products
(Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
Categories
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011].
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Featured LRP8 Categories
LRP8 Antibodies
High quality antibodies with extensive validation data.
LRP8 ELISA Kits
Reliable ELISA kits for a wide range of species.
LRP8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LRP8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken, Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN719426
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
Validations
- (4)
Cat. No.
ABIN7193275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (3)
Cat. No.
ABIN7439357
Quantity
100 μL
Datasheet
Datasheet
Recommended LRP8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968358
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957543
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593445
Quantity
96 tests
Datasheet
Datasheet
Recommended LRP8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309740
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407613
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7405202
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LRP8 products
: "Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural ..." in: Experimental neurology, Vol. 320, pp. 112970, (2019) (PubMed).: "Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2." in: Neurobiology of aging, Vol. 49, pp. 145-153, (2016) (PubMed).
: "PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain." in: Journal of lipid research, Vol. 51, Issue 9, pp. 2611-8, (2010) (PubMed).
: "Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain." in: Biochemistry, Vol. 42, Issue 35, pp. 10406-17, (2003) (PubMed).
: "The transmembrane domain and PXXP motifs of ApoE receptor 2 exclude it from carrying out clathrin-mediated endocytosis." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 19926-32, (2003) (PubMed).
: "Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue." in: The Journal of biological chemistry, Vol. 276, Issue 16, pp. 13192-7, (2001) (PubMed).
: "AAV serotypes have distinctive interactions with domains of the cellular receptor AAVR." in: Journal of virology (PubMed).
Synonyms and alternative names related to LRP8
LDL receptor related protein 8 (LRP8), low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (Lrp8), LDL receptor related protein 8 (Lrp8), 4932703M08Rik, AA921429, AI848122, APOER2, ApoER2, HSZ75190, Lr8b, LR8B, LRP-8, LRP8, MCI1Protein level used designations for LRP8
- low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
- low density lipoprotein receptor-related protein 8
- low-density lipoprotein receptor-related protein 8-like
- ApoE receptor 2
- low-density lipoprotein receptor-related protein 8
- apolipoprotein E receptor 2
- low density lipoprotein receptor relative, 8 ligand binding repeats, brain
- LRP-8
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