LRP6 Products
(Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
Categories
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
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Featured LRP6 Categories
LRP6 Antibodies
High quality antibodies with extensive validation data.
LRP6 ELISA Kits
Reliable ELISA kits for a wide range of species.
LRP6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LRP6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN7193277
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN6263009
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (2)
Cat. No.
ABIN390100
Quantity
400 μL
Datasheet
Datasheet
Recommended LRP6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957542
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6973692
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968357
Quantity
96 tests
Datasheet
Datasheet
Recommended LRP6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275210
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491293
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN6938849
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LRP6 products
: "A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6." in: Journal of pharmacological and toxicological methods, Vol. 95, pp. 47-55, (2019) (PubMed).: "Exercise training ameliorates bleomycin-induced epithelial mesenchymal transition and lung fibrosis through restoration of H2 S synthesis." in: Acta physiologica (Oxford, England), pp. e13177, (2018) (PubMed).
: "Expression of low-density lipoprotein-related receptors 5 and 6 (LRP5/6) in psoriasis skin." in: Experimental dermatology, Vol. 26, Issue 11, pp. 1033-1038, (2018) (PubMed).
: "FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation." in: Bone reports, Vol. 9, pp. 136-144, (2018) (PubMed).
: "Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma." in: Oncotarget, Vol. 8, Issue 14, pp. 22825-22834, (2017) (PubMed).
: "Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 249-59, (2016) (PubMed).
: "USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 21, pp. E2945-54, (2016) (PubMed).
: "Low neural exosomal levels of cellular survival factors in Alzheimer's disease." in: Annals of clinical and translational neurology, Vol. 2, Issue 7, pp. 769-73, (2015) (PubMed).
: "Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer." in: Oncogene, Vol. 34, Issue 38, pp. 4914-27, (2015) (PubMed).
: "Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 852-62, (2014) (PubMed).
Synonyms and alternative names related to LRP6
LDL receptor related protein 6 (LRP6), LDL receptor related protein 6 L homeolog (lrp6.L), LDL receptor related protein 6 S homeolog (lrp6.S), low density lipoprotein receptor-related protein 6 (lrp6), LDL receptor related protein 6 (lrp6), low density lipoprotein receptor-related protein 6 (Lrp6), LDL receptor related protein 6 (Lrp6), low-density lipoprotein receptor-related protein 6 (LOC590395), adcad2, ADCAD2, C030016K15Rik, Cd, Gw, lrp6, LRP6, lrp6-A, Xlrp6Protein level used designations for LRP6
- low density lipoprotein receptor-related protein 6
- lipoprotein receptor-related protein 6
- low-density lipoprotein receptor-related protein 6
- low-density lipoprotein receptor-related protein 6-like
- LRP-6
- crooked
- low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6
- low density lipoprotein-related protein 6
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