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LRP2 Proteins

(Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))

The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling\; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].

recommended

LRP2 Protein (AA 4035-4184) (His tag) (ABIN7397174)

LRP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC

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recommended

LRP2 Protein (AA 1186-1389, Extracellular) (His tag) (ABIN5713618)

LRP2 Origin: Human Host: Yeast Recombinant > 90 % SDS

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LRP2 Proteins by Origin

Find LRP2 Proteins for a variety of species such as anti-Human LRP2. The species listed below are among those available. Click on a link to go to the corresponding products.

LRP2 Proteins by Source

Here you will find LRP2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

LRP2 Proteins by Protein Type

Here you can find LRP2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

LRP2 Proteins by Application

Find LRP2 Proteins validated for a specific application such as SDS, Imm, PC, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular LRP2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

LRP2 Protein (AA 4035-4184) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7397174

Quantity 100 μg

Datasheet Datasheet

LRP2 Protein (AA 1186-1389, Extracellular) (His tag)

Reactivity Human

Source Yeast

Validations

Cat. No. ABIN5713618

Quantity 100 μg

Datasheet Datasheet

Aliases for LRP2 Proteins

LDL receptor related protein 2 (LRP2) Proteins
low density lipoprotein receptor-related protein 2a (lrp2a) Proteins
low density lipoprotein receptor-related protein 2 (LRP2) Proteins
low-density lipoprotein receptor-related protein 2 (LRP2.3) Proteins
LDL receptor related protein 2 L homeolog (lrp2.L) Proteins
low-density lipoprotein receptor-related protein 2 (LOC100183506) Proteins
LDL receptor related protein 2 (lrp2) Proteins
low density lipoprotein receptor-related protein 2 (Lrp2) Proteins
LDL receptor related protein 2 (Lrp2) Proteins
AI315343 Proteins
AW536255 Proteins
D230004K18Rik Proteins
dbs Proteins
DBS Proteins
gp330 Proteins
GP330 Proteins
Gp330 Proteins
im:680590 Proteins
lrp2 Proteins
megalin Proteins
Megalin Proteins

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LRP2 Proteins by Origin

LRP2 Proteins by Source

LRP2 Proteins by Protein Type

LRP2 Proteins by Application

Popular LRP2 Proteins

Aliases for LRP2 Proteins

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