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LRP1 Products

(Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Categories

The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010].

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Featured LRP1 Categories

LRP1 Antibodies

High quality antibodies with extensive validation data.

LRP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

LRP1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LRP1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (6)
Cat. No. ABIN3021969
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, FACS, ICC
Validations
  • (6)
Cat. No. ABIN5542496
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, FACS, IHC (p), IHC (fro), IF (p), IF (cc)
Validations
  • (4)
Cat. No. ABIN748988
Quantity 100 μL
Datasheet Datasheet

Recommended LRP1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6957535
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968349
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6968347
Quantity 96 tests
Datasheet Datasheet

Recommended LRP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309728
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392929
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423378
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LRP1 products

Wen, Tan, Dai, Zhu, Meng, Yang, Liu, Liu, Yuan, Hu: "VEGF-mediated tight junctions pathological fenestration enhances doxorubicin-loaded glycolipid-like nanoparticles traversing BBB for glioblastoma-targeting therapy." in: Drug delivery, Vol. 24, Issue 1, pp. 1843-1855, (2018) (PubMed).

Khodadadi, Gharakhanlou, Naghdi, Salimi, Azimi, Shahed, Heysieattalab: "Treadmill Exercise Ameliorates Spatial Learning and Memory Deficits Through Improving the Clearance of Peripheral and Central Amyloid-Beta Levels." in: Neurochemical research, Vol. 43, Issue 8, pp. 1561-1574, (2018) (PubMed).

Gonzalo-Calvo, Colom, Vilades, Rivas-Urbina, Moustafa, Pérez-Cuellar, Sánchez-Quesada, Pérez, LLorente-Cortes: "Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus." in: Scientific reports, Vol. 8, Issue 1, pp. 1054, (2018) (PubMed).

Kong, Han, Cui, Zhou, Jiang, Zhang, Wang, Wang, Zhang: "MCM2 mediates progesterone-induced endometrial stromal cell proliferation and differentiation in mice." in: Endocrine, Vol. 53, Issue 2, pp. 595-606, (2017) (PubMed).

de Gonzalo-Calvo, Vilades, Nasarre, Carreras, Leta, Garcia-Moll, Llorente-Cortes: "Circulating levels of soluble low-density lipoprotein receptor-related protein 1 (sLRP1) as novel biomarker of epicardial adipose tissue." in: International journal of cardiology, Vol. 223, pp. 371-373, (2016) (PubMed).

Kepa, Horvath, Reitter-Pfoertner, Schemper, Quehenberger, Grundbichler, Heistinger, Neumeister, Mannhalter, Pabinger: "Parameters influencing FVIII pharmacokinetics in patients with severe and moderate haemophilia A." in: Haemophilia : the official journal of the World Federation of Hemophilia, (2015) (PubMed).

Li, Wu, Zhao, Feng: "Effects and relationship of intermittent hypoxia on serum lipid levels, hepatic low-density lipoprotein receptor-related protein 1, and hypoxia-inducible factor 1α." in: Sleep & breathing = Schlaf & Atmung, (2015) (PubMed).

de Gonzalo-Calvo, Cenarro, Martínez-Bujidos, Badimon, Bayes-Genis, Ordonez-Llanos, Civeira, Llorente-Cortés: "Circulating soluble low-density lipoprotein receptor-related protein 1 (sLRP1) concentration is associated with hypercholesterolemia: A new potential biomarker for atherosclerosis." in: International journal of cardiology, Vol. 201, pp. 20-9, (2015) (PubMed).

Sen, Nelson, Alkon: "ApoE4 and A? Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 19, pp. 7538-51, (2015) (PubMed).

Li, Cheng, Cheng, Zhu, Wan, Liu, Zhang: "Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer's disease amyloid-β proteins." in: PLoS ONE, Vol. 9, Issue 6, pp. e99939, (2015) (PubMed).

Synonyms and alternative names related to LRP1

LDL receptor related protein 1 (LRP1), LDL receptor related protein 1 (Lrp1), prolow-density lipoprotein receptor-related protein 1 (LOC100414789), low density lipoprotein receptor-related protein 1 (Lrp1), A2MR, A2mr, AI316852, APOER, APR, CD91, IGFBP3R, LRP, Lrp, LRP-1, LRP1A, TGFBR5

Protein level used designations for LRP1

  • LRP-1
  • TbetaR-V/LRP-1/IGFBP-3 receptor
  • alpha-2-macroglobulin receptor
  • apolipoprotein E receptor
  • prolow-density lipoprotein receptor-related protein 1
  • type V tgf-beta receptor
  • low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)
  • low density lipoprotein receptor-related protein 1
  • prolow-density lipoprotein receptor-related protein 1-like
  • alpha 2-macroglobulin receptor
  • lipoprotein receptor-related protein
  • low-density lipoprotein receptor-related protein 1
  • low-density lipoprotein receptor-related protein/alpha-2 macroglobulin receptor
  • LOW QUALITY PROTEIN: prolow-density lipoprotein receptor-related protein 1
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