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Lrig1 Products

(Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation (By similarity).

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Featured Lrig1 Categories

Lrig1 Antibodies

High quality antibodies with extensive validation data.

Lrig1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Lrig1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Lrig1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN735263
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7158206
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN1881506
Quantity 400 μL
Datasheet Datasheet

Recommended Lrig1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730711
Quantity 96 tests
Datasheet Datasheet

Recommended Lrig1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275205
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275206
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275204
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Lrig1 products

Yui, Azzolin, Maimets, Pedersen, Fordham, Hansen, Larsen, Guiu, Alves, Rundsten, Johansen, Li, Madsen, Nakamura, Watanabe, Nielsen, Schweiger, Piccolo, Jensen: "YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration." in: Cell stem cell, Vol. 22, Issue 1, pp. 35-49.e7, (2018) (PubMed).

Singh, Camera, Krug, Basu, Pandey, Munir, Wlaschek, Kochanek, Schorpp-Kistner, Picardo, Angel, Niemann, Maity, Scharffetter-Kochanek: "JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin." in: Nature communications, Vol. 9, Issue 1, pp. 3425, (2018) (PubMed).

Murai, Skrupskelyte, Piedrafita, Hall, Kostiou, Ong, Nagy, Cagan, Goulding, Klein, Hall, Jones: "Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations." in: Cell stem cell, Vol. 23, Issue 5, pp. 687-699.e8, (2018) (PubMed).

Hoeck, Biehs, Kurtova, Kljavin, de Sousa E Melo, Alicke, Koeppen, Modrusan, Piskol, de Sauvage: "Stem cell plasticity enables hair regeneration following Lgr5+cell loss." in: Nature cell biology, Vol. 19, Issue 6, pp. 666-676, (2017) (PubMed).

Chovatiya, Sarate, Sunkara, Gawas, Kala, Waghmare: "Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response." in: Scientific reports, Vol. 7, Issue 1, pp. 11619, (2017) (PubMed).

Ge, Gomez, Adam, Nikolova, Yang, Verma, Lu, Polak, Yuan, Elemento, Fuchs: "Stem Cell Lineage Infidelity Drives Wound Repair and Cancer." in: Cell, Vol. 169, Issue 4, pp. 636-650.e14, (2017) (PubMed).

Yang, Dai, Tan, Zhang, Meng, Ye, Wang, Wei, He, Chen: "Lrig1 is a positive prognostic marker in hepatocellular carcinoma." in: OncoTargets and therapy, Vol. 9, pp. 7071-7079, (2016) (PubMed).

Zhao, Qiao, Zhang, Zhang, Lei, Wang, Deng, Ning, Cao, Guo, Liu, Duan: "GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing." in: Scientific reports, Vol. 5, pp. 7913, (2015) (PubMed).

Dahlhoff, Frances, Kloepper, Paus, Schäfer, Niemann, Schneider: "Overexpression of epigen during embryonic development induces reversible, epidermal growth factor receptor-dependent sebaceous gland hyperplasia." in: Molecular and cellular biology, Vol. 34, Issue 16, pp. 3086-95, (2014) (PubMed).

Oh, Lee, Choi, Suh, Shim, Song, Kim, Lee, Oh, Jeong, Cheong, Song, Kim: "USP8 modulates ubiquitination of LRIG1 for Met degradation." in: Scientific reports, Vol. 4, pp. 4980, (2014) (PubMed).

Synonyms and alternative names related to Lrig1

leucine rich repeats and immunoglobulin like domains 1 (LRIG1), leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1), D6Bwg0781e, Img, LIG-1, LIG1

Protein level used designations for Lrig1

  • leucine-rich repeat protein LRIG1
  • leucine-rich repeats and immunoglobulin-like domains protein 1
  • ortholog of mouse integral membrane glycoprotein LIG-1
  • integral membrane glycoprotein
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