LRBA Products
(LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA))
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The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].
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LRBA Antibodies
High quality antibodies with extensive validation data.
Recommended LRBA Antibodies
Recommended LRBA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5709875
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5709877
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LRBA products
: "Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity. ..." in: American journal of human genetics, Vol. 90, Issue 6, pp. 986-1001, (2012) (PubMed).: "LRBA gene deletion in a patient presenting with autoimmunity without hypogammaglobulinemia." in: The Journal of allergy and clinical immunology, Vol. 130, Issue 6, pp. 1428-32, (2012) (PubMed).
Synonyms and alternative names related to LRBA
LPS-responsive beige-like anchor (Lrba), LPS responsive beige-like anchor protein (LRBA), BGL, C80285, CDC4L, CVID8, D3Ertd775e, Lab300, LAB300, Lba, LBAProtein level used designations for LRBA
- beige-like protein
- lipopolysaccharide-responsive and beige-like anchor protein
- CDC4-like protein
- vesicle trafficking, beach and anchor containing
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