LOXL2 Products
(Lysyl Oxidase-Like 2 (LOXL2))
Categories
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008].
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Featured LOXL2 Categories
LOXL2 Antibodies
High quality antibodies with extensive validation data.
LOXL2 ELISA Kits
Reliable ELISA kits for a wide range of species.
LOXL2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LOXL2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, IHC (p), IF
Validations
- (5)
- (8)
Cat. No.
ABIN2856034
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7438565
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, FACS
Validations
- (5)
Cat. No.
ABIN7127602
Quantity
100 μL
Datasheet
Datasheet
Recommended LOXL2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6957604
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975613
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957605
Quantity
96 tests
Datasheet
Datasheet
Recommended LOXL2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309674
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7504457
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398506
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LOXL2 products
: "LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells. ..." in: Oncogene, Vol. 39, Issue 1, pp. 79-121, (2020) (PubMed).: "LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype." in: Frontiers in oncology, Vol. 10, pp. 284, (2020) (PubMed).
: "Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma." in: The Laryngoscope, Vol. 130, Issue 5, pp. E327-E334, (2020) (PubMed).
: "Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB." in: Oncogenesis, Vol. 8, Issue 5, pp. 34, (2019) (PubMed).
: "Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis." in: Disease models & mechanisms, Vol. 10, Issue 11, pp. 1301-1312, (2018) (PubMed).
: "The serum level and significance of lysyl oxidase-like 2 in patients with rheumatoid arthritis-associated interstitial lung disease." in: Clinical rheumatology, Vol. 37, Issue 1, pp. 193-198, (2018) (PubMed).
: "Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer." in: Oncology letters, Vol. 15, Issue 2, pp. 2431-2440, (2018) (PubMed).
: "Emerging role of LOXL2 in the promotion of pancreas cancer metastasis." in: Oncotarget, Vol. 7, Issue 27, pp. 42539-42552, (2018) (PubMed).
: "LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway." in: Scientific reports, Vol. 7, pp. 44988, (2018) (PubMed).
: "HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 60, (2018) (PubMed).
Synonyms and alternative names related to LOXL2
lysyl oxidase like 2 (LOXL2), lysyl oxidase-like 2 (lox2), lysyl oxidase-like 2 (Loxl2), lysyl oxidase homolog 4 (LOC408544), lysyl oxidase-like 2 (LOXL2), lysyl oxidase like 2 L homeolog (loxl2.L), lysyl oxidase like 2 (loxl2), lysyl oxidase like 2 (Loxl2), lysyl oxidase-like 2b (loxl2b), 1110004B06Rik, 4930526G11Rik, 9430067E15Rik, CG4402, Dmel\\CG4402, dmlox-2, Dmloxl-2, GB13360, im:7136137, LOR2, lor2, lox2-like, loxl-2, LOXL2, si:dkeyp-32b1.1, WS9-14, ws9-14, wu:fk12g04, zgc:158414Protein level used designations for LOXL2
- lysyl oxidase homolog 2
- lysyl oxidase related 2
- lysyl oxidase-like protein 2
- lysyl oxidase-related protein 2
- lysyl oxidase-related protein WS9-14
- CG4402-PA
- lox2-PA
- lysyl oxidase-like 2
- Lysyl oxidase-like protein 2
- lysyl oxidase homolog 2-like
- Lysyl oxidase homolog 2
- Lysyl oxidase-like protein 2B
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