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LOXL1 Products

(Lysyl Oxidase-Like 1 (LOXL1))

Categories

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008].

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Featured LOXL1 Categories

LOXL1 Antibodies

High quality antibodies with extensive validation data.

LOXL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

LOXL1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LOXL1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7436069
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (2)
Cat. No. ABIN517560
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP, IF
Validations
  • (3)
Cat. No. ABIN948090
Quantity 100 μL
Datasheet Datasheet

Recommended LOXL1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6957602
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957603
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593939
Quantity 96 tests
Datasheet Datasheet

Recommended LOXL1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400942
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398497
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398500
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LOXL1 products

Tjin, White, Faiz, Sicard, Tschumperlin, Mahar, Kable, Burgess: "Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis." in: Disease models & mechanisms, Vol. 10, Issue 11, pp. 1301-1312, (2018) (PubMed).

Gayathri, Coral, Sharmila, Sripriya, Sripriya, Manish, Shantha, Ronnie, Vijaya, Narayanasamy: "Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation." in: Current eye research, Vol. 41, Issue 10, pp. 1331-1338, (2016) (PubMed).

Aung, Ozaki, Mizoguchi, Allingham, Li, Haripriya, Nakano, Uebe, Harder, Chan, Lee, Burdon, Astakhov, Abu-Amero, Zenteno, Nilgün, Zarnowski, Pakravan, Safieh, Jia, Wang, Williams, Paoli, Schlottmann et al.: "A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. ..." in: Nature genetics, Vol. 47, Issue 4, pp. 387-92, (2015) (PubMed).

Coral, Madhavan, Pukhraj, Angayarkanni: "High glucose induced differential expression of lysyl oxidase and its isoform in ARPE-19 cells." in: Current eye research, Vol. 38, Issue 1, pp. 194-203, (2013) (PubMed).

Sethi, Wordinger, Clark: "Gremlin utilizes canonical and non-canonical TGF? signaling to induce lysyl oxidase (LOX) genes in human trabecular meshwork cells." in: Experimental eye research, Vol. 113, pp. 117-27, (2013) (PubMed).

Schlötzer-Schrehardt, Hammer, Krysta, Hofmann-Rummelt, Pasutto, Sasaki, Kruse, Zenkel: "LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma." in: Ophthalmology, Vol. 119, Issue 9, pp. 1832-43, (2012) (PubMed).

Ohmura, Yasukawa, Minami, Sugi, Oba, Nagata, Kyogoku, Ohshima, Aoki, Imaizumi: "Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 35, Issue 11, pp. 1063-8, (2012) (PubMed).

Sethi, Mao, Wordinger, Clark: "Transforming growth factor-beta induces extracellular matrix protein cross-linking lysyl oxidase (LOX) genes in human trabecular meshwork cells." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5240-50, (2011) (PubMed).

Trackman: "Diverse biological functions of extracellular collagen processing enzymes." in: Journal of cellular biochemistry, Vol. 96, Issue 5, pp. 927-37, (2005) (PubMed).

Mki, Sormunen, Lippo, Kaarteenaho-Wiik, Soininen, Myllyharju: "Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues." in: The American journal of pathology, Vol. 167, Issue 4, pp. 927-36, (2005) (PubMed).

Synonyms and alternative names related to LOXL1

lysyl oxidase like 1 (LOXL1), lysyl oxidase like 1 (loxl1), lysyl oxidase-like 1 (Loxl1), lysyl oxidase-like 1 (loxl1), lysyl oxidase like 1 L homeolog (loxl1.L), LOL, lol, LOXL, Loxl, loxl, loxl-1, oxl-1, si:ch211-238c15.1

Protein level used designations for LOXL1

  • lysyl oxidase-like 1
  • lysyl oxidase homolog 1-like
  • lysyl oxidase homolog 1
  • lysyl oxidase-like protein 1
  • lysyl oxidase 2
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