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LOX Proteins

(Lysyl Oxidase (LOX))

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].

recommended

LOX Protein (Myc-DYKDDDDK Tag) (ABIN2712316)

LOX Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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recommended

LOX Protein (AA 174-417) (His tag) (ABIN7123817)

LOX Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

LOX Protein (His tag) (ABIN7413259)

LOX Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

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LOX Proteins by Origin

Find LOX Proteins for a variety of species such as anti-Human LOX, anti-Mouse LOX, anti-Chicken LOX. The species listed below are among those available. Click on a link to go to the corresponding products.

LOX Proteins by Source

Here you will find LOX Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

LOX Proteins by Protein Type

Here you can find LOX Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

LOX Proteins by Application

Find LOX Proteins validated for a specific application such as ELISA, SDS, WB, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LOX Proteins by Biological Activity

Find LOX Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular LOX Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

LOX Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

(12)
(1)

Cat. No. ABIN2712316

Quantity 20 μg

Datasheet Datasheet

LOX Protein (AA 174-417) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7123817

Quantity 50 μg

Datasheet Datasheet

LOX Protein (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7413259

Quantity 100 μg

Datasheet Datasheet

LOX Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2130388

Quantity 100 μg

Datasheet Datasheet

LOX Protein (AA 213-417) (His tag,GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7396547

Quantity 100 μg

Datasheet Datasheet

LOX Protein (AA 169-417) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7424992

Quantity 100 μg

Datasheet Datasheet

LOX Protein (AA 207-411) (His tag,GST tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7396550

Quantity 100 μg

Datasheet Datasheet

LOX Protein (AA 213-417) (His tag,GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6239913

Quantity 50 μg

Datasheet Datasheet

LOX Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3010561

Quantity 100 μg

Datasheet Datasheet

LOX Protein (DYKDDDDK-His Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2725073

Quantity 20 μg

Datasheet Datasheet

LOX Protein (AA 163-411) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1476047

Quantity 1 mg

Datasheet Datasheet

LOX Protein (AA 172-420) (His tag)

Reactivity Chicken

Source Yeast

Validations

Cat. No. ABIN1458763

Quantity 1 mg

Datasheet Datasheet

LOX Protein (AA 1-249) (His tag)

Reactivity Pig

Source Yeast

Validations

Cat. No. ABIN1472498

Quantity 1 mg

Datasheet Datasheet

LOX Protein (AA 170-418) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1459811

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our LOX Proteins

Pilecki, Holm, Schlosser, Moeller, Wohl, Zuk, Heumüller, Wallis, Moestrup, Sengle, Holmskov, Sorensen: "Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation." in: The Journal of biological chemistry, Vol. 291, Issue 3, pp. 1103-14, (2016) (PubMed).

Kondala, Puri, Banka, Sachdeva, Sakhuja: "Short-term prognosis of potential celiac disease in Indian patients." in: United European gastroenterology journal, Vol. 4, Issue 2, pp. 275-80, (2016) (PubMed).

Tsukasaki, Hamada, Okamoto, Nagashima, Terashima, Komatsu, Win, Okamura, Nitta, Yasuda, Penninger, Takayanagi: "LOX Fails to Substitute for RANKL in Osteoclastogenesis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 32, Issue 3, pp. 434-439, (2016) (PubMed).

Cox, Rumney, Schoof, Perryman, Høye, Agrawal, Bird, Latif, Forrest, Evans, Huggins, Lang, Linding, Gartland, Erler: "The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase." in: Nature, Vol. 522, Issue 7554, pp. 106-10, (2015) (PubMed).

Miller, Morton, Pinese, Saturno, Jamieson, McGhee, Timpson, Leach, McGarry, Shanks, Bailey, Chang, Oien, Karim, Au, Steele, Carter, McKay, Anderson, Evans, Marais, Springer, Biankin, Erler, Sansom: "Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy." in: EMBO molecular medicine, Vol. 7, Issue 8, pp. 1063-76, (2015) (PubMed).

Richter, Dayaram, Gilmartin, Ganji, Pemmasani, Van Der Key, Shohet, Donehower, Kumar: "WIP1 phosphatase as a potential therapeutic target in neuroblastoma." in: PLoS ONE, Vol. 10, Issue 2, pp. e0115635, (2015) (PubMed).

Zhao, Sagare, Ma, Halliday, Kong, Kisler, Winkler, Ramanathan, Kanekiyo, Bu, Owens, Rege, Si, Ahuja, Zhu, Miller, Schneider, Maeda, Maeda, Sugawara, Ichida, Zlokovic: "Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance." in: Nature neuroscience, Vol. 18, Issue 7, pp. 978-87, (2015) (PubMed).

Arnold, Kent, Hogarth, Schlatt, Prasad, Haenisch, Walsh, Muller, Griswold, Amory, Isoherranen: "Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations." in: Journal of lipid research, Vol. 56, Issue 2, pp. 342-57, (2015) (PubMed).

Wilson, Bradley, Shaw, Wagenmakers: "Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature." in: Histochemistry and cell biology, Vol. 142, Issue 3, pp. 245-56, (2014) (PubMed).

Nandhu, Hu, Cole, Erdreich-Epstein, Rodriguez-Gil, Viapiano: "Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas." in: Cancer research, Vol. 74, Issue 19, pp. 5435-48, (2014) (PubMed).

Aliases for LOX Proteins

lysyl oxidase (LOX) Proteins
lysyl oxidase (lox) Proteins
lysyl oxidase a (loxa) Proteins
lysyl oxidase L homeolog (lox.L) Proteins
lysyl oxidase (Lox) Proteins
AI893619 Proteins
H-rev142 Proteins
LOX Proteins
lox Proteins
MGC146507 Proteins
Rrg1 Proteins
TSC-160 Proteins
Xlox Proteins
zgc:77447 Proteins

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LOX Proteins by Origin

LOX Proteins by Source

LOX Proteins by Protein Type

LOX Proteins by Application

LOX Proteins by Biological Activity

Popular LOX Proteins

Latest Publications for our LOX Proteins

Aliases for LOX Proteins

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