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Low Density Lipoprotein Receptor Proteins

(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
LDLR Protein (AA 22-788) (His tag) LDLR Protein (AA 22-788) (His tag) LDLR Protein (AA 22-788) (His tag) (ABIN7275138)

LDLR Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

LDLR Protein (AA 22-788) (His-Avi Tag) LDLR Protein (AA 22-788) (His-Avi Tag) LDLR Protein (AA 22-788) (His-Avi Tag) (ABIN7275139)

LDLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

LDLR Protein (AA 105-205) (GST tag) LDLR Protein (AA 105-205) (GST tag) LDLR Protein (AA 105-205) (GST tag) (ABIN1309277)

LDLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Low Density Lipoprotein Receptor Proteins by Grade

Find Low Density Lipoprotein Receptor Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor Proteins by Origin

Find Low Density Lipoprotein Receptor Proteins for a variety of species such as anti-Human Low Density Lipoprotein Receptor, anti-Mouse Low Density Lipoprotein Receptor, anti-Cynomolgus Low Density Lipoprotein Receptor. The species listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor Proteins by Source

Here you will find Low Density Lipoprotein Receptor Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Low Density Lipoprotein Receptor Proteins by Protein Type

Here you can find Low Density Lipoprotein Receptor Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Low Density Lipoprotein Receptor Proteins by Application

Find Low Density Lipoprotein Receptor Proteins validated for a specific application such as WB, ELISA, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor Proteins by Biological Activity

Find Low Density Lipoprotein Receptor Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Low Density Lipoprotein Receptor Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275138
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275139
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1309277
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7275140
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN5526601
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN2181455
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123785
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7491325
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1780661
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320327
Quantity 50 μg
Datasheet Datasheet
Reactivity Rabbit
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7013410
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN2870752
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN5954921
Quantity 200 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505399
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
Cat. No. ABIN7505737
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Low Density Lipoprotein Receptor Proteins

Basak, Verghese, Yoon, Kim, Holtzman: "Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of A? uptake and degradation by astrocytes." in: The Journal of biological chemistry, Vol. 287, Issue 17, pp. 13959-71, (2012) (PubMed).

Prunotto, Carnevali, Candiano, Murtas, Bruschi, Corradini, Trivelli, Magnasco, Petretto, Santucci, Mattei, Gatti, Scolari, Kador, Allegri, Ghiggeri: "Autoimmunity in membranous nephropathy targets aldose reductase and SOD2." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 507-19, (2010) (PubMed).

Aliases for Low Density Lipoprotein Receptor Proteins

low density lipoprotein receptor (LDLR) Proteins
low density lipoprotein receptor (Ldlr) Proteins
low density lipoprotein receptor a (ldlra) Proteins
low density lipoprotein receptor S homeolog (ldlr.S) Proteins
low density lipoprotein receptor L homeolog (ldlr.L) Proteins
FH Proteins
FHC Proteins
fhc Proteins
Hlb301 Proteins
LDLA Proteins
LDLCQ2 Proteins
ldlcq2 Proteins
ldlr Proteins
ldlr-a Proteins
ldlr-b Proteins
ldlr2-a Proteins
LDLRA Proteins
LDL receptor-2 Proteins
LDL receptor 1 Proteins
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