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LMTK2 Products

(Lemur tyrosine Kinase 2 (LMTK2))
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009].

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Featured LMTK2 Categories

LMTK2 Antibodies

High quality antibodies with extensive validation data.

LMTK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

LMTK2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LMTK2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6258874
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN524806
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN391208
Quantity 400 μL
Datasheet Datasheet

Recommended LMTK2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648270
Quantity 96 tests
Datasheet Datasheet

Recommended LMTK2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309527
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134993
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our LMTK2 products

Shah, Bradbury: "Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy." in: Oncotarget, Vol. 6, Issue 16, pp. 14233-46, (2015) (PubMed).

Zheng, Hsing, Sun, Chu, Yu, Li, Gao, Kim, Isaacs, Shen, Gao, Hoover, Xu: "Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men." in: The Prostate, Vol. 70, Issue 4, pp. 425-32, (2010) (PubMed).

Kawa, Fujimoto, Tezuka, Nakazawa, Yamamoto: "Involvement of BREK, a serine/threonine kinase enriched in brain, in NGF signalling." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 9, Issue 3, pp. 219-32, (2004) (PubMed).

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

Synonyms and alternative names related to LMTK2

lemur tyrosine kinase 2 (LMTK2), lemur tyrosine kinase 2 (Lmtk2), 2900041G10Rik, A330101P12Rik, AATYK2, aatyk2, BREK, cprk, KPI-2, KPI2, LMR2

Protein level used designations for LMTK2

  • CDK5/p35-regulated kinase
  • apoptosis-associated tyrosine kinase 2
  • brain-enriched kinase
  • cyclin-dependent kinase 5/p35-regulated kinase
  • hBREK
  • kinase phosphatase inhibitor 2
  • kinase/phosphatase/inhibitor 2
  • serine/threonine-protein kinase KPI-2
  • serine/threonine-protein kinase LMTK2
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