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LLGL2 Products

(Lethal Giant Larvae Homolog 2 (LLGL2))

Categories

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured LLGL2 Categories

LLGL2 Antibodies

High quality antibodies with extensive validation data.

LLGL2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended LLGL2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
  • (4)
Cat. No. ABIN561680
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7264313
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN948088
Quantity 100 μL
Datasheet Datasheet

Recommended LLGL2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309484
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309482
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3093413
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our LLGL2 products

Dong, Zhang, Liu, Chen, Huang, Austin, Celotto, Jiang, Palladino, Jiang, Hammond, Hong: "A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia." in: The Journal of cell biology, Vol. 211, Issue 2, pp. 273-86, (2015) (PubMed).

Patil, Bennett, Mahajan, Bronner: "Distinguishing Barrett gastric foveolar dysplasia from reactive cardiac mucosa in gastroesophageal reflux disease." in: Human pathology, Vol. 44, Issue 6, pp. 1146-53, (2013) (PubMed).

Norman, Wisniewska, Lawrenson, Garcia-Miranda, Tada, Kajita, Mano, Ishikawa, Ikegawa, Shimada, Fujita: "Loss of Scribble causes cell competition in mammalian cells." in: Journal of cell science, Vol. 125, Issue Pt 1, pp. 59-66, (2012) (PubMed).

Russ, Louderbough, Zarnescu, Schroeder: "Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation." in: PLoS ONE, Vol. 7, Issue 10, pp. e47734, (2012) (PubMed).

Cong, Hirose, Harita, Yamashita, Mizuno, Hirano, Ohno: "ASPP2 regulates epithelial cell polarity through the PAR complex." in: Current biology : CB, Vol. 20, Issue 15, pp. 1408-14, (2010) (PubMed).

Tamori, Bialucha, Tian, Kajita, Huang, Norman, Harrison, Poulton, Ivanovitch, Disch, Liu, Deng, Fujita: "Involvement of Lgl and Mahjong/VprBP in cell competition." in: PLoS biology, Vol. 8, Issue 7, pp. e1000422, (2010) (PubMed).

Yasumi, Sakisaka, Hoshino, Kimura, Sakamoto, Yamanaka, Ohno, Takai: "Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6761-5, (2005) (PubMed).

Katoh, Katoh: "Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico." in: International journal of oncology, Vol. 24, Issue 3, pp. 737-42, (2004) (PubMed).

Synonyms and alternative names related to LLGL2

LLGL2, scribble cell polarity complex component L homeolog (llgl2.L), LLGL2, scribble cell polarity complex component (llgl2), lethal giant larvae homolog 2 (Drosophila) (llgl2), LLGL2, scribble cell polarity complex component (LLGL2), lethal giant larvae homolog 2 (Drosophila) (Llgl2), LLGL2, scribble cell polarity complex component (Llgl2), 9130006H11Rik, cb521, hgl, HGL, lgl-2, Lgl-2, lgl2, LGL2, llglh2, Llglh2, RGD1560307, sb:cb521, wu:fc06g08, wu:fl37c09, zgc:55895

Protein level used designations for LLGL2

  • lethal giant larvae 2
  • lethal giant larva 2
  • lethal(2) giant larvae protein homolog 2
  • pen
  • penner
  • protein penner
  • human giant larvae homolog
  • lethal giant larvae-like protein 2
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