LIN28B Proteins

(Lin-28 Homolog B (LIN28B))

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012].

Recommended next Filters:

All filter options

Would you like to try our new AI Search?

Show Filters

6 results

LIN28B Protein (AA 1-250) (His tag)

custom-made LIN28B Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant LIN28B Protein, UniprotID Q6ZN17

3 images

Catalog No. ABIN7554422

Details

LIN28B Protein (AA 1-247) (His tag)

custom-made LIN28B Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)