LIMS1 Products
(LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
Categories
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
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Featured LIMS1 Categories
LIMS1 Antibodies
High quality antibodies with extensive validation data.
LIMS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LIMS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LIMS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (2)
- (5)
Cat. No.
ABIN969354
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7158341
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7237326
Quantity
200 μL
Datasheet
Datasheet
Recommended LIMS1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957478
Quantity
96 tests
Datasheet
Datasheet
Recommended LIMS1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309446
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309444
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7405864
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LIMS1 products
: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).: "The structural basis of integrin-linked kinase-PINCH interactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, (2008) (PubMed).
: "Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury." in: Glia, Vol. 41, Issue 3, pp. 213-23, (2003) (PubMed).
: "The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells." in: Molecular and cellular biology, Vol. 19, Issue 3, pp. 2425-34, (1999) (PubMed).
: "Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways." in: Molecular biology of the cell, Vol. 9, Issue 12, pp. 3367-82, (1999) (PubMed).
Synonyms and alternative names related to LIMS1
LIM zinc finger domain containing 1 (LIMS1), LIM zinc finger domain containing 1 (Lims1), LIM and senescent cell antigen-like domains 1 (Lims1), 2310016J22Rik, 4921524A02Rik, AI507642, AU021743, AW551584, C430041B13Rik, Lims1l, LIMS3, LIMS3L, PINCH, PINCH-1, PINCH1, Pinch1, RGD1560732Protein level used designations for LIMS1
- LIM and senescent cell antigen-like-containing domain protein 1
- particularly interesting new Cys-His protein 1
- renal carcinoma antigen NY-REN-48
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