LILRB3 Products
(Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))
Categories
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured LILRB3 Categories
LILRB3 Antibodies
High quality antibodies with extensive validation data.
LILRB3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LILRB3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7440167
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
Cat. No.
ABIN7158272
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7440143
Quantity
100 μL
Datasheet
Datasheet
Recommended LILRB3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951591
Quantity
96 tests
Datasheet
Datasheet
Recommended LILRB3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275189
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275190
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320154
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LILRB3 products
: "CAMKs support development of acute myeloid leukemia." in: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 30, (2018) (PubMed).: "Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation." in: Nature communications, Vol. 4, pp. 2990, (2014) (PubMed).
: "Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development." in: Nature, Vol. 485, Issue 7400, pp. 656-60, (2012) (PubMed).
: "SIRP?/CD172a regulates eosinophil homeostasis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2268-77, (2011) (PubMed).
: "Cytokine induced expression of programmed death ligands in human neutrophils." in: Immunology letters, Vol. 129, Issue 2, pp. 100-7, (2010) (PubMed).
: "Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers." in: Journal of virology, Vol. 84, Issue 18, pp. 9463-71, (2010) (PubMed).
: "Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients." in: Blood, Vol. 114, Issue 11, pp. 2323-32, (2009) (PubMed).
: "Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 43, pp. 13503-15, (2009) (PubMed).
: "Inhibitory immunoglobulin-like receptors LILRB and PIR-B negatively regulate osteoclast development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 7, pp. 4742-51, (2008) (PubMed).
: "Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation." in: The Journal of experimental medicine, Vol. 204, Issue 4, pp. 907-20, (2007) (PubMed).
Synonyms and alternative names related to LILRB3
leukocyte immunoglobulin like receptor B3 (LILRB3), paired Ig-like receptor B (Pirb), leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), CD85A, Gp91, HL9, ILT-5, ILT5, LILRA6, Lilrb3, LILRB3, LIR-3, LIR3, NILR-1, PIR-B, PIRB, PirbProtein level used designations for LILRB3
- CD85 antigen-like family member A
- immunoglobulin-like transcript 5
- leukocyte immunoglobulin-like receptor 3
- leukocyte immunoglobulin-like receptor subfamily B member 3
- leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
- monocyte inhibitory receptor HL9
- cell-surface glycoprotein p91
- leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
- paired immunoglobulin-like receptor B
- paired-Ig-like receptor B
- type 1 one-pass transmembrane Ig-like receptor
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