LILRA3 Products
(Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))
Categories
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM, Mar 2008].
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Featured LILRA3 Categories
LILRA3 Antibodies
High quality antibodies with extensive validation data.
LILRA3 ELISA Kits
Reliable ELISA kits for a wide range of species.
LILRA3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LILRA3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
Cat. No.
ABIN5684140
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
- (2)
Cat. No.
ABIN564777
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7433585
Quantity
100 μL
Datasheet
Datasheet
Recommended LILRA3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957468
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5690906
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386023
Quantity
96 tests
Datasheet
Datasheet
Recommended LILRA3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275178
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7275177
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309410
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our LILRA3 products
: "Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66." in: Journal of cell science, Vol. 129, Issue 6, pp. 1198-209, (2016) (PubMed).: "Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not ..." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149200, (2016) (PubMed).
: "TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads." in: Retrovirology, Vol. 13, pp. 15, (2016) (PubMed).
: "Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 32873-85, (2013) (PubMed).
: "Soluble LILRA3, a potential natural antiinflammatory protein, is increased in patients with rheumatoid arthritis and is tightly regulated by interleukin 10, tumor necrosis factor-alpha, and ..." in: The Journal of rheumatology, Vol. 37, Issue 8, pp. 1596-606, (2010) (PubMed).
: "DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3." in: Immunogenetics, Vol. 55, Issue 3, pp. 165-71, (2003) (PubMed).
: "A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 11, pp. 5192-6, (1998) (PubMed).
: "Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2342-9, (1997) (PubMed).
Synonyms and alternative names related to LILRA3
leukocyte immunoglobulin like receptor A3 (LILRA3), CD85E, e3, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4Protein level used designations for LILRA3
- CD85 antigen-like family member E
- immunoglobulin-like transcript 6
- leucocyte immunoglobulin-like receptor
- leukocyte immunoglobulin-like receptor 4
- leukocyte immunoglobulin-like receptor A3
- leukocyte immunoglobulin-like receptor subfamily A member 3
- monocyte inhibitory receptor HM43/HM31
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