LIG1 Products
(Ligase I, DNA, ATP-Dependent (LIG1))
Categories
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq, Jul 2008].
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Featured LIG1 Categories
LIG1 Antibodies
High quality antibodies with extensive validation data.
LIG1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LIG1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LIG1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN7268251
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN561671
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN3022638
Quantity
100 μL
Datasheet
Datasheet
Recommended LIG1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968292
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6216170
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6216167
Quantity
96 tests
Datasheet
Datasheet
Recommended LIG1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1309400
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2719545
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414489
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LIG1 products
: "DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase." in: Nucleic acids research, Vol. 47, Issue 5, pp. 2402-2424, (2019) (PubMed).: "Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex." in: The EMBO journal, Vol. 34, Issue 13, pp. 1829-43, (2015) (PubMed).
: "Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity." in: Biochemistry, Vol. 50, Issue 11, pp. 1901-9, (2011) (PubMed).
: "DNA polymerase beta-dependent long patch base excision repair in living cells." in: DNA repair, Vol. 9, Issue 2, pp. 109-19, (2010) (PubMed).
: "Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity." in: Nucleic acids research, Vol. 37, Issue 10, pp. 3431-41, (2009) (PubMed).
: "Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks." in: Nucleic acids research, Vol. 36, Issue 10, pp. 3297-310, (2008) (PubMed).
: "Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells." in: The Journal of pharmacology and experimental therapeutics, Vol. 321, Issue 1, pp. 318-26, (2007) (PubMed).
: "A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22721-30, (2007) (PubMed).
: "Low levels of DNA ligases III and IV sufficient for effective NHEJ." in: Journal of cellular physiology, Vol. 213, Issue 2, pp. 475-83, (2007) (PubMed).
: "Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20865-72, (2006) (PubMed).
Synonyms and alternative names related to LIG1
DNA ligase 1 (LIG1), DNA ligase 1 (PB000674.02.0), DNA ligase 1 (PTRG_06243), DNA ligase 1, putative (PKH_140260), ligase I, DNA, ATP-dependent L homeolog (lig1.L), ligase I, DNA, ATP-dependent (Lig1), DNA ligase 1 (Lig1), DNA ligase 1 (lig-1), ligase I, DNA, ATP-dependent (lig1), AL033288, ATLIG1, DNA ligase 1, lig1, ligI, LigI, T6D22.23, wu:fc54a11Protein level used designations for LIG1
- DNA ligase 1
- polydeoxyribonucleotide synthase [ATP] 1
- DNA ligase (ATP) 1
- DNA ligase I
- LIG1, ligase I, DNA, ATP-dependent
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